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Saliva and plasma l...
Saliva and plasma levels of cardiac-related biomarkers in post-myocardial infarction patients.
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Rathnayake, N (author)
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- Buhlin, K (author)
- Karolinska Institutet
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Kjellström, B (author)
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- Klinge, Björn (author)
- Malmö högskola,Odontologiska fakulteten (OD)
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- Löwbeer, C (author)
- Karolinska Institutet
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- Norhammar, A (author)
- Karolinska Institutet
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- Rydén, L (author)
- Karolinska Institutet
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- Sorsa, T (author)
- Karolinska Institutet
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Tervahartiala, T (author)
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- Gustafsson, A (author)
- Karolinska Institutet
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Lindahl, B (author)
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Nygren, Å (author)
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- Näsman, Per (author)
- KTH,Transportplanering, ekonomi och teknik
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Svenungsson, E (author)
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(creator_code:org_t)
- 2017-06-20
- 2017
- English.
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In: Journal of Clinical Periodontology. - : Blackwell. - 0303-6979 .- 1600-051X. ; 44:7, s. 692-699
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http://rdcu.be/x3LQ/
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Aim: To relate cardiac biomarkers, such as cystatin C and growth differentiation factor-15 (GDF-15) in saliva to myocardial infarction (MI) and to periodontal status, and to investigate the relation between salivary and plasma cardiac biomarkers. Materials and Methods: Two hundred patients with MI admitted to coronary care units and 200 matched controls without MI were included. Dental examination and collection of blood and saliva samples was performed 6–10 weeks after the MI for patients and in close proximity thereafter for controls. Analysing methods: ARCHITECT i4000SR, Immulite 2000 XPi or ELISA. Results: The mean age was 62 ± 8 years and 84% were male. Total probing pocket depth, fibrinogen, white blood cell counts and HbA1c were higher in patients than controls. GDF-15 levels correlated with most of the included clinical variables in both study groups. No correlation was found between plasma and saliva levels of cystatin C or GDF-15. Conclusion: Salivary cystatin C and GDF-15 could not differentiate between MI patients and controls.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Keyword
- acute myocardial infarction; cystatin C; growth differentiation factor-15; periodontal disease; plasma; saliva
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Rathnayake, N
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Buhlin, K
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Kjellström, B
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Klinge, Björn
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Löwbeer, C
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Norhammar, A
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show more...
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Rydén, L
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Sorsa, T
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Tervahartiala, T
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Gustafsson, A
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Lindahl, B
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Nygren, Å
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Näsman, Per
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Svenungsson, E
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dentistry
- Articles in the publication
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Journal of Clini ...
- By the university
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Royal Institute of Technology
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Malmö University
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Karolinska Institutet