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Pressure and flow properties of cannulae for extracorporeal membrane oxygenation II : drainage (venous) cannulae

Broman, Lars Mikael (author)
Karolinska Institutet
Prahl Wittberg, Lisa, Docent, 1978- (author)
KTH,Linné Flow Center, FLOW,BioMEx
Westlund, C. Jerker (author)
Karolinska Univ Hosp, Dept Pediat Perioperat Med & Intens Care, ECMO Ctr Karolinska, S-17176 Stockholm, Sweden.
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Gilbers, Martijn (author)
Maastricht Univ, Hosp Med, Cardiovasc Res Inst Maastricht CARIM, Heart & Vasc Ctr,Dept Cardiothorac Surg, Maastricht, Netherlands.;Maastricht Univ, Dept Physiol, Maastricht, Netherlands.
da Camara, Luisa Perry (author)
Hosp Curry Cabral, Ctr Hosp Lisboa Cent, Lisbon, Portugal.
Westin, Jan (author)
Karolinska Univ Hosp, Dept Med Technol, Stockholm, Sweden.
Taccone, Fabio Silvio (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;ULB, Dept Intens Care, Hop Erasme, Brussels, Belgium.
Malfertheiner, Maximilian Valentin (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Med Ctr Regensburg, Dept Internal Med Cardiol & Pneumol 2, Regensburg, Germany.
Di Nardo, Matteo (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Childrens Hosp Bambino Gesu, IRCCS, Pediat Intens Care Unit, Rome, Italy.
Swol, Justyna (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Paracelsus Med Univ, Dept Pulmonol, Intens Care Med, Nurnberg, Germany.
Vercaemst, Leen (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Hosp Gasthuisberg, Dept Perfus, Louven, Belgium.
Barrett, Nicholas A. (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Guys & St Thomas NHS Fdn Trust, Dept Crit Care, London, England.;Guys & St Thomas NHS Fdn Trust, Severe Resp Failure Serv, London, England.
Pappalardo, Federico (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Vita Salute San Raffaele, Hosp San Raffaele, Adv Heart Failure & Mech Circulatory Support Prog, Milan, Italy.
Belohlavek, Jan (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Charles Univ Prague, Dept Med 2, Dept Cardiovasc Med, Gen Univ Hosp Prague, Prague, Czech Republic.;Charles Univ Prague, Fac Med 1, Prague, Czech Republic.
Mueller, Thomas (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Med Ctr Regensburg, Dept Internal Med Cardiol & Pneumol 2, Regensburg, Germany.
Belliato, Mirko (author)
EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Fdn IRCCS Policlin San Matteo, UOC Anestesia & Rianimaz 1, Pavia, Italy.
Lorusso, Roberto (author)
KTH,BioMEx,Linné Flow Center, FLOW,EuroELSO, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England
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 (creator_code:org_t)
2019-04-10
2019
English.
In: Perfusion. - : SAGE PUBLICATIONS LTD. - 0267-6591 .- 1477-111X. ; 34, s. 65-73
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The use of extracorporeal life support devices such as extracorporeal membrane oxygenation in adults requires cannulation of the patient's vessels with comparatively large diameter cannulae to allow circulation of large volumes of blood (>5 L/min). The cannula diameter and length are the major determinants for extracorporeal membrane oxygenation flow. Manufacturing companies present pressure-flow charts for the cannulae; however, these tests are performed with water. Aims of this study were 1. to investigate the specified pressure-flow charts obtained when using human blood as the circulating medium and 2. to support extracorporeal membrane oxygenation providers with pressure-flow data for correct choice of the cannula to reach an optimal flow with optimal hydrodynamic performance. Eighteen extracorporeal membrane oxygenation drainage cannulae, donated by the manufacturers (n = 6), were studied in a centrifugal pump driven mock loop. Pressure-flow properties and cannula features were described. The results showed that when blood with a hematocrit of 27% was used, the drainage pressure was consistently higher for a given flow (range 10%-350%) than when water was used (data from each respective manufacturer's product information). It is concluded that the information provided by manufacturers in line with regulatory guidelines does not correspond to clinical performance and therefore may not provide the best guidance for clinicians.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine (hsv//eng)

Keyword

drainage
cannula
pressure
flow
extracorporeal membrane oxygenation
extracorporeal
life support
venous

Publication and Content Type

ref (subject category)
art (subject category)

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