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AVRA :
AVRA : Automatic visual ratings of atrophy from MRI images using recurrent convolutional neural networks
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- Mårtensson, Gustav (author)
- Karolinska Institutet
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- Ferreira, Daniel (author)
- Karolinska Institutet
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- Cavallin, Lena (author)
- Karolinska Institutet
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- Muehlboeck, J-Sebastian (author)
- Karolinska Institutet
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- Wahlund, Lars-Olof (author)
- Karolinska Institutet
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- Wang, Chunliang, 1980- (author)
- KTH,Medicinsk avbildning
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- Westman, Eric (author)
- Karolinska Institutet
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(creator_code:org_t)
- ELSEVIER SCI LTD, 2019
- 2019
- English.
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In: NeuroImage. - : ELSEVIER SCI LTD. - 2213-1582. ; 23
- Related links:
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https://doi.org/10.1...
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http://adni.loni.usc...
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Abstract
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- Quantifying the degree of atrophy is done clinically by neuroradiologists following established visual rating scales. For these assessments to be reliable the rater requires substantial training and experience, and even then the rating agreement between two radiologists is not perfect. We have developed a model we call AVRA (Automatic Visual Ratings of Atrophy) based on machine learning methods and trained on 2350 visual ratings made by an experienced neuroradiologist. It provides fast and automatic ratings for Scheltens' scale of medial temporal atrophy (MTA), the frontal subscale of Pasquier's Global Cortical Atrophy (GCA-F) scale, and Koedam's scale of Posterior Atrophy (PA). We demonstrate substantial inter-rater agreement between AVRA's and a neuroradiologist ratings with Cohen's weighted kappa values of kappa(w) = 0.74/0.72 (MTA left/right), kappa(w) = 0.62 (GCA-F) and kappa(w) = 0.74 (PA). We conclude that automatic visual ratings of atrophy can potentially have great scientific value, and aim to present AVRA as a freely available toolbox.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- Atrophy
- Visual ratings
- Machine learning
- MRI
- Neuroimaging
- Radiology
Publication and Content Type
- ref (subject category)
- art (subject category)
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