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- Stöber, T M (author)
Selective neuromodulation and mutual inhibition within the CA3–CA2 system can prioritize sequences for replay
- Article/chapterEnglish2020
Publisher, publication year, extent ...
- 2020-09
- Wiley,2020
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:kth-284865
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-284865URI
- https://doi.org/10.1002/hipo.23256DOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- QC 20201203
- To make optimal use of previous experiences, important neural activity sequences must be prioritized during hippocampal replay. Integrating insights about the interplay between CA3 and CA2, we propose a conceptual framework that allows the two regions to control which sequences are reactivated. We suggest that neuromodulatory-gated plasticity and mutual inhibition enable discrete assembly sequences in both regions to support each other while suppressing competing sequences. This perspective provides a coherent interpretation for a variety of seemingly disconnected functional properties of CA2 and paves the way for a more general understanding of CA2.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Neurovetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Neurosciences hsv//eng
- CA2
- CA3
- conceptual framework
- consolidation
- controlled study
- hippocampal CA2 region
- hippocampal CA3 region
- hippocampus
- human
- neuromodulation
- note
- sequence prioritization
Added entries (persons, corporate bodies, meetings, titles ...)
- Lehr, A B (author)
- Hafting, T (author)
- Kumar, ArvindKTH,Beräkningsvetenskap och beräkningsteknik (CST)(Swepub:kth)u1vukjbl (author)
- Fyhn, M (author)
- KTHBeräkningsvetenskap och beräkningsteknik (CST) (creator_code:org_t)
Related titles
- In:Hippocampus: Wiley30:11, s. 1228-12381050-96311098-1063
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- Stöber, T M
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- Fyhn, M
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
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- Hippocampus
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- Royal Institute of Technology
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