SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:DiVA.org:kth-287138"
 

Search: onr:"swepub:oai:DiVA.org:kth-287138" > A One Step Procedur...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Eslami, M. (author)

A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2020-06-15
  • Wiley,2020
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:kth-287138
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-287138URI
  • https://doi.org/10.1002/mabi.202000103DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • QC 20201203
  • Interaction of conjugated polymers with liposomes is an attractive approach that benefits from both systems’ characteristics such as electroactivity and enhanced interaction with cells. Conjugated polymer-liposome complexes have been investigated for bioimaging, drug delivery, and photothermal therapy. Their fabrication has largely been achieved by multistep procedures that require first the synthesis and processing of the conjugated polymer. Here, a new one step fabrication approach is reported based on in situ polymerization of a conjugated monomer precursor around liposomes. Polyaniline (PANI) doped with phytic acid is synthesized via oxidative polymerization in the presence of 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) vesicles to produce a conductive aqueous suspension of Liposome-PANI complexes. PANI interacts with liposomes without disrupting the bilayer as shown using differential scanning calorimetry and fluorescence quenching studies of the hydrophobic Nile red probe. The electronic conductivity of the Liposome-PANI complexes, which stems from the doped PANI accessible on the liposome surface, is confirmed using conductive atomic force microscopy and electrochemical impedance spectroscopy. Further, short-term in vitro cell studies show that the complexes colocalize with the cell membrane without reducing cell proliferation. This study presents a novel fabrication route to conductive suspensions of conjugated polymer-liposome complexes suitable for potential applications at the biointerface.

Subject headings and genre

  • NATURVETENSKAP Kemi Polymerkemi hsv//swe
  • NATURAL SCIENCES Chemical Sciences Polymer Chemistry hsv//eng
  • complex
  • conductive suspensions
  • conjugated polymers
  • liposomes
  • Cell proliferation
  • Cells
  • Cytology
  • Differential scanning calorimetry
  • Electrochemical impedance spectroscopy
  • Polymerization
  • Quenching
  • Suspensions (fluids)
  • Synthesis (chemical)
  • Conductive atomic force microscopy
  • Electronic conductivity
  • In-situ polymerization
  • Multi-step procedures
  • Oxidative polymerization
  • Photothermal therapy
  • Polyaniline complexes
  • Synthesis and processing
  • Drug delivery

Added entries (persons, corporate bodies, meetings, titles ...)

  • Zeglio, EricaKTH,Mikro- och nanosystemteknik(Swepub:kth)u140hbga (author)
  • Alosaimi, G. (author)
  • Yan, Y. (author)
  • Ruprai, H. (author)
  • Macmillan, A. (author)
  • Seidel, J. (author)
  • Lauto, A. (author)
  • Joukhdar, H. (author)
  • Rnjak-Kovacina, J. (author)
  • Mawad, D. (author)
  • KTHMikro- och nanosystemteknik (creator_code:org_t)

Related titles

  • In:Macromolecular Bioscience: Wiley20:111616-51871616-5195

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view