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- Gustafsson, AnnaLund University,Lunds universitet,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH (author)
Subject-specific FE models of the human femur predict fracture path and bone strength under single-leg-stance loading
- Article/chapterEnglish2021
Publisher, publication year, extent ...
- Elsevier BV,2021
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:kth-288642
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-288642URI
- https://doi.org/10.1016/j.jmbbm.2020.104118DOI
- https://lup.lub.lu.se/record/bd0f620d-f1d5-4329-a5dc-47003c47fa66URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- QC 20210112
- Hip fractures are a major health problem with high socio-economic costs. Subject-specific finite element (FE) models have been suggested to improve the fracture risk assessment, as compared to clinical tools based on areal bone mineral density, by adding an estimate of bone strength. Typically, such FE models are limited to estimate bone strength and possibly the fracture onset, but do not model the fracture process itself. The aim of this study was to use a discrete damage approach to simulate the full fracture process in subject-specific femur models under stance loading conditions. A framework based on the partition of unity finite element method (PUFEM), also known as XFEM, was used. An existing PUFEM framework previously used on a homogeneous generic femur model was extended to include a heterogeneous material description together with a strain-based criterion for crack initiation. The model was tested on two femurs, previously mechanically tested in vitro. Our results illustrate the importance of implementing a subject-specific material distribution to capture the experimental fracture pattern under stance loading. Our models accurately predicted the fracture pattern and bone strength (1% and 5% error) in both investigated femurs. This is the first study to simulate complete fracture paths in subject-specific FE femur models and it demonstrated how discrete damage models can provide a more complete picture of fracture risk by considering both bone strength and fracture toughness in a subject-specific fashion.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
- TEKNIK OCH TEKNOLOGIER Medicinteknik Medicinsk material- och protesteknik hsv//swe
- ENGINEERING AND TECHNOLOGY Medical Engineering Medical Materials hsv//eng
- Partition of unity
- PUFEM
- XFEM
- Cohesive traction separation law
- Crack surface
- Crack propagation
- Cohesive traction separation law
- Crack propagation
- Crack surface
- Partition of unity
- PUFEM
- XFEM
Added entries (persons, corporate bodies, meetings, titles ...)
- Tognini, MartinaLund Univ, Dept Biomed Engn, Box 118, S-22100 Lund, Sweden.,Lund University (author)
- Bengtsson, FridaLund Univ, Dept Biomed Engn, Box 118, S-22100 Lund, Sweden.,Lund University (author)
- Gasser, T. ChristianKTH Royal Institute of Technology,KTH,Hållfasthetslära(Swepub:kth)u1dvxi4s (author)
- Isaksson, HannaLund University,Lunds universitet,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Building Bone Killing Bugs,Forskargrupper vid Lunds universitet,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,Lund University Research Groups(Swepub:lu)soli-hai (author)
- Grassi, LorenzoLund University,Lunds universitet,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)soli-glo (author)
- Institutionen för biomedicinsk teknikInstitutioner vid LTH (creator_code:org_t)
Related titles
- In:Journal of The Mechanical Behavior of Biomedical Materials: Elsevier BV1131751-61611878-0180
Internet link
- https://doi.org/10.1016/j.jmbbm.2020.104118Fulltext
- https://doi.org/10.1016/j.jmbbm.2020.104118
- http://dx.doi.org/10.1016/j.jmbbm.2020.104118FULLTEXT
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-288642
- https://doi.org/10.1016/j.jmbbm.2020.104118
- https://lup.lub.lu.se/record/bd0f620d-f1d5-4329-a5dc-47003c47fa66
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