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Commentary The new era of quantitative cell imaging-challenges and opportunities

Bagheri, Neda (author)
Allen Inst Cell Sci, Seattle, WA 98109 USA.;Univ Washington, Biol & Chem Engn, Seattle, WA 98195 USA.
Carpenter, Anne E. (author)
Broad Inst Harvard & MIT, Imaging Platform, Cambridge, MA 02142 USA.
Lundberg, Emma (author)
KTH,Science for Life Laboratory, SciLifeLab,Cellulär och klinisk proteomik
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Plant, Anne L. (author)
NIST, Gaithersburg, MD 20899 USA.
Horwitz, Rick (author)
Allen Inst Cell Sci, Seattle, WA 98109 USA.
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Allen Inst Cell Sci, Seattle, WA 98109 USA;Univ Washington, Biol & Chem Engn, Seattle, WA 98195 USA. Broad Inst Harvard & MIT, Imaging Platform, Cambridge, MA 02142 USA. (creator_code:org_t)
Elsevier BV, 2022
2022
English.
In: Molecular Cell. - : Elsevier BV. - 1097-2765 .- 1097-4164. ; 82:2, s. 241-247
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Quantitative optical microscopy-an emerging, transformative approach to single-cell biology-has seen dramatic methodological advancements over the past few years. However, its impact has been hampered by challenges in the areas of data generation, management, and analysis. Here we outline these technical and cultural challenges and provide our perspective on the trajectory of this field, ushering in a new era of quantitative, data-driven microscopy. We also contrast it to the three decades of enormous advances in the field of genomics that have significantly enhanced the reproducibility and wider adoption of a plethora of genomic approaches.

Subject headings

NATURVETENSKAP  -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)

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