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Semi-automated prep...
Semi-automated preparation of fine-needle aspiration samples for rapid on-site evaluation
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- Marques, Filipe (author)
- KTH,Mikro- och nanosystemteknik
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- Hauser, Janosch (author)
- KTH,Mikro- och nanosystemteknik
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- Iseri, Emre (author)
- KTH,Mikro- och nanosystemteknik
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- Schliemann, Igor (author)
- Pathology and Cytology Department, Karolinska University Hospital, Stockholm, Sweden
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- van der Wijngaart, Wouter (author)
- KTH,Mikro- och nanosystemteknik
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- Roxhed, Niclas (author)
- KTH,Mikro- och nanosystemteknik,Medtech Labs, Karolinska hospital, Stockholm, Sweden
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(creator_code:org_t)
- 2022
- 2022
- English.
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In: Lab on a Chip. - : Royal Society of Chemistry (RSC). - 1473-0197 .- 1473-0189. ; 22, s. 2192-2199
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Rapid on-site evaluation (ROSE) significantly improves the diagnostic yield of fine needle aspiration (FNA) samples but critically depends on the skills and availability of cytopathologists. Here, we introduce a portable device for semi-automated sample preparation for ROSE. In a single platform, the device combines a smearing tool and a capillary-driven chamber for staining FNA samples. Using a human pancreatic cancer cell line (PANC-1) and liver, lymph node, and thyroid FNA model samples, we demonstrate the capability of the device to prepare samples for ROSE. By minimizing the equipment needed in the operating room, the device may simplify the performance of FNA sample preparation and lead to a wider implementation of ROSE.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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