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  • Chireh, A.Karolinska Institutet (author)

Safety evaluation of high-risk myocardial micro-biopsy in a swine model

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • 2021-11-23
  • Springer Nature,2022
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:kth-313197
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-313197URI
  • https://doi.org/10.1007/s00380-021-01995-9DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:148168074URI

Supplementary language notes

  • Language:English
  • Summary in:English

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Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • QC 20220607
  • The objective of the study was to investigate the safety profile of high-risk micro-endomyocardial biopsy (micro-EMB) compared to conventional EMB in a large animal model. Twenty pigs were subjected to a maximum of 30 consecutive biopsies, including sampling from the free ventricular wall, with either micro-EMB (n = 10) or conventional EMB (n = 10). There were no major complications in the micro-EMB group (0/10), compared to six major complications in the EMB group (6/10; p = 0.003). Survival analysis further highlighted these differences (p = 0.004). There were significantly higher volumes of pericardial effusion in the EMB group (p = 0.01). The study shows a safety advantage of micro-EMB compared to standard EMB in the experimental high-risk circumstances investigated in this animal study. These results indicate enhanced possibilities to collect samples from sensitive areas by using the micro-EMB technique instead of standard EMB. 

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Sandell, MikaelKTH,Mikro- och nanosystemteknik,Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; MedTechLabs, Solna, Sweden(Swepub:kth)u13uy6zj (author)
  • Grankvist, R.Karolinska Institutet (author)
  • Lövljung, V. (author)
  • al-Saadi, J. (author)
  • Arnberg, F.Karolinska Institutet (author)
  • Lundberg, J.Karolinska Institutet (author)
  • Settergren, M.Karolinska Institutet (author)
  • Holmin, S.Karolinska Institutet (author)
  • Karolinska InstitutetMikro- och nanosystemteknik (creator_code:org_t)

Related titles

  • In:Heart and Vessels: Springer Nature37:4, s. 697-7040910-83271615-2573

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