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Copper(II) chloride...
Copper(II) chloride as an efficient reagent for the dehydrogenation of pyridazinone derivatives
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Csende, F. (author)
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- Szabó, Zoltan, Associate professor (author)
- Inst. of Pharmaceutical Chemistry, Albert Szent-Gyorgyi Medical Univ., H-6701 Szeged, POB 121, Hungary
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Bernath, G. (author)
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Stajer, G. (author)
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Inst of Pharmaceutical Chemistry, Albert Szent-Gyorgyi Medical Univ., H-6701 Szeged, POB 121, Hungary (creator_code:org_t)
- Georg Thieme Verlag KG, 1995
- 1995
- English.
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In: Synthesis (Stuttgart). - : Georg Thieme Verlag KG. - 0039-7881 .- 1437-210X. ; :10, s. 1240-1242
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A new procedure is described for the preparation of pyridazinones from 4,5-dihydropyridazinones under mild conditions with CuCl2 in MeCN via halogenation and spontaneous HCl elimination. For the trans-hexahydrophthalazin-8(1H)-one 1B*, the HCl elimination is five times faster than for the corresponding cis isomer 1B.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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