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Array-Based Multipl...
Array-Based Multiplex and High-Throughput Serology Assays
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- Olofsson, Jennie (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik
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- Hellström, Ceke (författare)
- KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab
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- Andersson, Eni (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik
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- Yousef, Jamil (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik
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- Skoglund, Lovisa (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik
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- Sjöberg, Ronald (författare)
- KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab
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- Månberg, Anna, 1985- (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik
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- Nilsson, Peter (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik
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- Pin, Elisa (författare)
- KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab
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(creator_code:org_t)
- 2023-02-12
- 2023
- Engelska.
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Ingår i: Methods in Molecular Biology. - New York, NY : Springer Nature. - 1064-3745 .- 1940-6029. ; 2628, s. 535-553
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The detection of antibody responses using serological tests provides means to diagnose infections, follow disease transmission, and monitor vaccination responses. The coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 virus, highlighted the need for rapid development of robust and reliable serological tests to follow disease spreading. Moreover, the rise of SARS-CoV-2 variants emphasized the need to monitor their transmission and prevalence in the population. For this reason, multiplex and flexible serological assays are needed to allow for rapid inclusion of antigens representing new variants as soon as they appear. In this chapter, we describe the generation and application of a multiplex serological test, based on bead array technology, to detect anti-SARS-CoV-2 antibodies in a high-throughput manner, using only a few microliters of sample. This method is currently expanding to include a multi-disease antigen panel that will allow parallel detection of antibodies towards several infectious agents.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Nyckelord
- Antibody
- High-throughput
- Multiplex
- Plasma
- Protein array
- SARS-CoV-2
- Serology
- Serum
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Olofsson, Jennie
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Hellström, Ceke
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Andersson, Eni
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Yousef, Jamil
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Skoglund, Lovisa
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Sjöberg, Ronald
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visa fler...
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Månberg, Anna, 1 ...
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Nilsson, Peter
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Pin, Elisa
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinsk biotek ...
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och Medicinsk biotek ...
- Artiklar i publikationen
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Methods in Molec ...
- Av lärosätet
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Kungliga Tekniska Högskolan