SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:DiVA.org:kth-333884"
 

Search: onr:"swepub:oai:DiVA.org:kth-333884" > Next generation pan...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Alvez, Maria BuenoKTH,Science for Life Laboratory, SciLifeLab,Systembiologi,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden. (author)

Next generation pan-cancer blood proteome profiling using proximity extension assay

  • Article/chapterEnglish2023

Publisher, publication year, extent ...

  • Springer Nature,2023
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:kth-333884
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-333884URI
  • https://doi.org/10.1038/s41467-023-39765-yDOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-510006URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-197562URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:153432843URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • QC 20230815
  • Funding Agencies|Knut and Alice Wallenberg Foundation; SciLifeLab amp; Wallenberg Data Driven Life Science Program [KAW 2020.0239]; Swedish Research Council [2018-05973, 2020-06175]
  • A comprehensive characterization of blood proteome profiles in cancer patients can contribute to a better understanding of the disease etiology, resulting in earlier diagnosis, risk stratification and better monitoring of the different cancer subtypes. Here, we describe the use of next generation protein profiling to explore the proteome signature in blood across patients representing many of the major cancer types. Plasma profiles of 1463 proteins from more than 1400 cancer patients are measured in minute amounts of blood collected at the time of diagnosis and before treatment. An open access Disease Blood Atlas resource allows the exploration of the individual protein profiles in blood collected from the individual cancer patients. We also present studies in which classification models based on machine learning have been used for the identification of a set of proteins associated with each of the analyzed cancers. The implication for cancer precision medicine of next generation plasma profiling is discussed.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Edfors, FredrikKTH,Science for Life Laboratory, SciLifeLab,Systembiologi,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.(Swepub:kth)u149ml0e (author)
  • von Feilitzen, KalleKTH,Systembiologi,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.(Swepub:kth)u1dbmi38 (author)
  • Zwahlen, MartinKTH,Science for Life Laboratory, SciLifeLab,Systembiologi,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.(Swepub:kth)u1fcjpxe (author)
  • Mardinoglu, AdilKTH,Science for Life Laboratory, SciLifeLab,Systembiologi,Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King’s College London, London, SE1 9RT, UK,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.;Kings Coll London, Fac Dent Oral & Craniofacial Sci, Ctr Host Microbiome Interact, London SE1 9RT, England.(Swepub:kth)u1t8kmr6 (author)
  • Edqvist, Per HenrikDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden (author)
  • Sjöblom, TobiasUppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala Univ, Sweden(Swepub:uu)tobisjob (author)
  • Lundin, EmmaUppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala Univ, Sweden (author)
  • Rameika, NatalliaDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden(Swepub:uu)natra473 (author)
  • Enblad, GunillaUppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala Univ, Sweden(Swepub:uu)gunienbl (author)
  • Lindman, HenrikUppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala Univ, Sweden(Swepub:uu)henrlind (author)
  • Höglund, MartinUppsala universitet,Institutionen för medicinska vetenskaper,Uppsala Univ, Sweden(Swepub:uu)martinhl (author)
  • Hesselager, GöranDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden(Swepub:uu)goranhlr (author)
  • Stålberg, KarinUppsala universitet,Institutionen för kvinnors och barns hälsa,Uppsala Univ, Sweden(Swepub:uu)kariglim (author)
  • Enblad, MalinUppsala universitet,Institutionen för kirurgiska vetenskaper,Uppsala Univ, Sweden(Swepub:uu)malen817 (author)
  • Simonson, OscarUppsala universitet,Institutionen för kirurgiska vetenskaper,Uppsala Univ, Sweden(Swepub:uu)oscsi921 (author)
  • Häggman, MichaelUppsala universitet,Institutionen för kirurgiska vetenskaper,Uppsala Univ, Sweden(Swepub:uu)michhagg (author)
  • Axelsson, TomasUppsala universitet,Institutionen för medicinska vetenskaper,Uppsala Univ, Dept Med Sci, Clin Chem & SciLifeLab Affin Prote, Uppsala, Sweden.(Swepub:uu)toaxe957 (author)
  • Åberg, MikaelUppsala universitet,Science for Life Laboratory, SciLifeLab,Klinisk kemi,Uppsala Univ, Sweden(Swepub:uu)miabe173 (author)
  • Nordlund, JessicaUppsala universitet,Institutionen för medicinska vetenskaper,Uppsala Univ, Sweden(Swepub:uu)jesno775 (author)
  • Zhong, WenLinköpings universitet,Avdelningen för cellbiologi,Medicinska fakulteten,Science for Life Laboratory(Swepub:liu)wenzh16 (author)
  • Karlsson, MaxKTH,Systembiologi,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.(Swepub:kth)u1hm1ssx (author)
  • Gyllensten, Ulf B.Uppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala Univ, Dept Immunol Genet & Pathol, Uppsala, Sweden.(Swepub:uu)ulfgyll (author)
  • Ponten, FredrikUppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala Univ, Sweden(Swepub:uu)fredpont (author)
  • Fagerberg, LinnKTH,Science for Life Laboratory, SciLifeLab,Systembiologi,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.(Swepub:kth)u1dglfid (author)
  • Uhlén, MathiasKTH,Science for Life Laboratory, SciLifeLab,Systembiologi,Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden,KTH Royal Inst Technol, Dept Prot Sci, Sci Life Lab, Stockholm, Sweden.;Karolinska Inst, Dept Neurosci, Stockholm, Sweden.(Swepub:kth)u1dulvmw (author)
  • peedq227, Per-Henrik DUppsala universitet,Institutionen för immunologi, genetik och patologi(Swepub:uu)peedq227 (author)
  • KTHScience for Life Laboratory, SciLifeLab (creator_code:org_t)

Related titles

  • In:Nature Communications: Springer Nature14:12041-1723

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view