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QVALITY :
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Käll, Lukas,1969-Stockholms universitet,Institutionen för biokemi och biofysik
(author)
QVALITY : non-parametric estimation of q-values and posterior error probabilities
- Article/chapterEnglish2009
Publisher, publication year, extent ...
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2009-02-04
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Oxford University Press (OUP),2009
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:kth-48846
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https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-48846URI
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https://doi.org/10.1093/bioinformatics/btp021DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-34714URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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QC 20111124
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Qvality is a C++ program for estimating two types of standard statistical confidence measures: the q-value, which is an analog of the p-value that incorporates multiple testing correction, and the posterior error probability (PEP, also known as the local false discovery rate), which corresponds to the probability that a given observation is drawn from the null distribution. In computing q-values, qvality employs a standard bootstrap procedure to estimate the prior probability of a score being from the null distribution; for PEP estimation, qvality relies upon non-parametric logistic regression. Relative to other tools for estimating statistical confidence measures, qvality is unique in its ability to estimate both types of scores directly from a null distribution, without requiring the user to calculate p-values.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Storey, John D.
(author)
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Noble, William Stafford
(author)
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Stockholms universitetInstitutionen för biokemi och biofysik
(creator_code:org_t)
Related titles
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In:Bioinformatics: Oxford University Press (OUP)25:7, s. 964-9661367-48031367-4811
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