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Search: onr:"swepub:oai:DiVA.org:kth-6522" > The assessment of a...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003744naa a2200517 4500
001oai:DiVA.org:kth-6522
003SwePub
008061206s2006 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-153034
009oai:prod.swepub.kib.ki.se:1946973
024a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-65222 URI
024a https://doi.org/10.1088/0967-3334/27/12/0032 DOI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1530342 URI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:19469732 URI
040 a (SwePub)kthd (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Söderqvist, Emilu Department of Medical Engineering, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:kth)u197v88m
2451 0a The assessment of acute load and contractility changes by left ventricular pressure measurements
264 c 2006-10-25
264 1b IOP Publishing,c 2006
338 a print2 rdacarrier
500 a QC 20100922
520 a The aim of this study was to establish whether analysis of the left ventricular pressure waveform provides indicative information about cardiac load and contractility and to develop an algorithm for computer-based assessment of changes in these variables. In eight healthy standard breed anaesthetized open-chest pigs, a high frequency response guide-wire mounted pressure sensor was introduced into the left ventricle. Preload reduction was induced by vena cava occlusion, afterload increase by an i.v. injection of phenylephrine and increased contractility by an i.v. injection of adrenalin. Left ventricular pressure waveform analysis was performed by plotting the slope of the pressure curve during the systolic ejection period versus maximal systolic pressure. The analysis revealed characteristic changes in left ventricular pressure and pressure waveform and identified easily discernible reaction patterns in the slope versus maximal pressure plot, specific for each provocation. Analysis of the left ventricular waveform provides indicative information about loading conditions and contractility. The proposed algorithm can easily be implemented in pressure monitoring systems allowing real-time assessment and discrimination of acute changes in preload, afterload and myocardial performance.
650 7a TEKNIK OCH TEKNOLOGIERx Medicinteknikx Medicinsk laboratorie- och mätteknik0 (SwePub)206012 hsv//swe
650 7a ENGINEERING AND TECHNOLOGYx Medical Engineeringx Medical Laboratory and Measurements Technologies0 (SwePub)206012 hsv//eng
653 a monitoring
653 a left ventricle
653 a pressure waves
653 a loading conditions
653 a contractility
653 a Medical engineering
653 a Medicinsk teknik
653 a MEDICINE
700a Hultman, Janu Uppsala universitet,Institutionen för kirurgiska vetenskaper4 aut
700a Källner, Göranu Karolinska Institutet4 aut
700a Nowak, Jaceku Karolinska Institutet4 aut
700a Brodin, Lars-Åkeu Karolinska Institutet4 aut0 (Swepub:kth)u1jq9s27
710a Department of Medical Engineering, Karolinska Institutet, Stockholm, Swedenb Institutionen för kirurgiska vetenskaper4 org
773t Physiological Measurementd : IOP Publishingg 27:12, s. 1281-1292q 27:12<1281-1292x 0967-3334x 1361-6579
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-6522
8564 8u https://doi.org/10.1088/0967-3334/27/12/003
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-153034
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:1946973

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