Asymmetric [2,3]-sigmatropic rearrangement of allylic ammonium ylides

• An asymmetric Lewis acid-mediated [2,3]-sigmatropic rearrangement of allylic amines has been developed, affording the corresponding homoallylic amines in good yield and excellent enantioselectivities. The rearrangement proceeds by complexation of the chiral Lewis acid to the amine followed by deprotonation and rearrangement.

Subject headings

NATURVETENSKAP  -- Kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)

Keyword

allyl compound

ammonium derivative

article

chirality

diastereoisomer

quantum yield

reaction analysis

stereochemistry

Chemistry

Kemi

Publication and Content Type

ref (subject category)

art (subject category)