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Method for enhancing the immunogenicity of an immunogenic compound or hapten, and use thereof for preparing vaccines

Binz, Hans (author)
Nguyen, Thien Ngoc (author)
Andreoni, Christine (author)
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Nygren, Per-Åke, 1961- (author)
KTH,Bioteknologi,Nygren
Ståhl, Stefan (author)
Uhlén, Mathias (author)
KTH,Bioteknologi
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 (creator_code:org_t)
1994
English.
  • Patent (pop. science, debate, etc.)
Abstract Subject headings
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  • The present invention relates to a process for improving the immunogenicity of an immunogen, an antigen or a hapten, when it is administered to a host, independently of the mode of administration, characterized in that the said antigen or hapten is coupled covalently to a support molecule in order to form a complex, and in that this support molecule is a polypeptide fragment which is able to bind specifically to mammalian serum albumin. The invention also relates to the use, as a medicament, of the product which can be obtained in this way.

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