Surface Functionalization of Porous Resorbable Scaffolds by Covalent Grafting

QC 20100804. Uppdaterad från Submitted till Published 20100804.
Resorbable porous scaffold discs and solid films were prepared from poly[(1,5-dioxepan-2one)-co-(L-lactide)] and poly [(epsilon-caprolactone)-co-(L-lactide)]. The surfaces of the scaffolds were functionalized to increase their hydrophilicity. A total of 90 samples were prepared to cover all important combinations of experimental and material factors, and all experimental data were fitted by a partial least square model. As a result of grafting, the porous discs and solid films exhibited a tremendous increase in wettability. The functionalized discs were hygroscopic so that water was instantly absorbed and thoroughly wet the substrates.

NATURVETENSKAP Kemi Polymerkemi hsv//swe
NATURAL SCIENCES Chemical Sciences Polymer Chemistry hsv//eng
Biocompatibility; Functionalization of polymers; Grafting; Scaffolds; Surface modification; ABS resins; Biocompatibility; Curve fitting; Film preparation; Functional polymers; Grafting (chemical); Ketones; Surfaces; Caprolactone; Covalent grafting; Experimental datum; Functionalization of polymers; Functionalized; Grafting; Lactide; Material factors; Partial least square models; Porous scaffolds; Solid films; Surface functionalization; Surface modification; 1
5 benzodioxepane derivative; molecular scaffold; polycaprolactone; polylactide; lactide caprolactone copolymer; lactide-caprolactone copolymer; polyester; water; article; chemical binding; controlled study; covalent grafting; hydrophilicity; partial least squares regression; porosity; surface property; water absorption; wettability; absorption; chemistry; hydrophobicity; Absorption; Hydrophobicity; Polyesters; Porosity; Water; Wettability
Polymer chemistry
Polymerkemi

Edlund, UlricaKTH,Fiber- och polymerteknologi(Swepub:kth)u1goaund (author)
Albertsson, Ann-ChristineKTH,Fiber- och polymerteknologi(Swepub:kth)u1mpsp3u (author)
KTHFiber- och polymerteknologi (creator_code:org_t)

By the author/editor: Källrot, Martina; Edlund, Ulrica; Albertsson, Ann- ...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...; and Polymer Chemistr ...

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