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Small-animal tomogr...
Small-animal tomography with a liquid-metal-jet x-ray source
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- Larsson, Daniel H. (author)
- KTH,Biomedicinsk fysik och röntgenfysik
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- Lundström, Ulf (author)
- KTH,Biomedicinsk fysik och röntgenfysik
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Westermark, U. (author)
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- Takman, Per (author)
- KTH,Biomedicinsk fysik och röntgenfysik
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- Burvall, Anna (author)
- KTH,Biomedicinsk fysik och röntgenfysik
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Arsenian Henriksson, M. (author)
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- Hertz, Hans M. (author)
- KTH,Biomedicinsk fysik och röntgenfysik
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(creator_code:org_t)
- SPIE - International Society for Optical Engineering, 2012
- 2012
- English.
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In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. - : SPIE - International Society for Optical Engineering. - 9780819489623 ; , s. 83130N-
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- X-ray tomography of small animals is an important tool for medical research. For high-resolution x-ray imaging of few-cm-thick samples such as, e.g., mice, high-brightness x-ray sources with energies in the few-10-keV range are required. In this paper we perform the first small-animal imaging and tomography experiments using liquid-metal-jet-anode x-ray sources. This type of source shows promise to increase the brightness of microfocus x-ray systems, but present sources are typically optimized for an energy of 9 keV. Here we describe the details of a high-brightness 24-keV electron-impact laboratory microfocus x-ray source based on continuous operation of a heated liquid-In/Ga-jet anode. The source normally operates with 40 W of electron-beam power focused onto the metal jet, producing a 7×7 μm 2 FWHM x-ray spot. The peak spectral brightness is 4 × 10 9 photons/( s × mm 2 × mrad 2 × 0.1%BW) at the 24.2 keV In K α line. We use the new In/Ga source and an existing Ga/In/Sn source for high-resolution imaging and tomography of mice.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- liquid-metal-jet-anode
- mouse
- Small-animal imaging
- tomography
- x-ray
Publication and Content Type
- ref (subject category)
- kon (subject category)
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