Search: onr:"swepub:oai:DiVA.org:liu-113908" >
Serological evidenc...
Serological evidence for protection by human papillomavirus (HPV) type 6 infection against HPV type 16 cervical carcinogenesis.
-
- Silins, Ilvars (author)
- Microbiology and Tumor Biology Center, Karolinska Institute, Box 280, S-171 77 Stockholm, Sweden
-
- Wang, Zhaohui (author)
- Microbiology and Tumor Biology Center, Karolinska Institute, Box 280, S-171 77 Stockholm, Sweden
-
- Åvall Lundqvist, Elisabeth (author)
- Karolinska Institutet,Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Department of Gynaecologic Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden
-
show more...
-
- Frankendal, Bo (author)
- Department of Gynaecologic Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden
-
- Vikmanis, Uldis (author)
- University of Latvia, Riga, Latvia
-
- Sapp, Martin (author)
- Department of Medical Microbiology, University of Mainz, Mainz, Germany
-
- Schiller, John T (author)
- Laboratory of Cellular Oncology, The National Cancer Institute, Bethesda, MD, USA
-
- Dillner, Joakim (author)
- Karolinska Institutet
-
show less...
-
(creator_code:org_t)
- Microbiology Society, 1999
- 1999
- English.
-
In: Journal of General Virology. - : Microbiology Society. - 0022-1317 .- 1465-2099. ; 80:11, s. 2931-2936
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://urn.kb.se/re...
-
http://kipublication...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Human papillomavirus (HPV) exists as more than 100 genotypes. It is not well-established whether the different HPV types interfere with infection or pathogenesis by each other. Possible interactions in cervical carcinogenesis between infection with the most common HPV types (6, 11, 16, 18 and 33) were studied in a seroepidemiological case- control study of 218 women with primary untreated cervical cancer and 219 healthy age-matched control women. As previously shown, HPV-16 seropositivity was associated with cervical cancer risk [odds ratio (OR), 2.39], but HPV-16 was not associated with cervical cancer risk among HPV-6 seropositive women (OR, 1.0). The relative excess risk due to interaction between HPV-6 and -16 was -2. 35 (95% confidence interval, -0.04 to -4.65), indicating significant antagonism. The results suggest that infection with HPV-6 may interfere with HPV-16-associated cervical carcinogenesis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database