Non-contact scanning diffuse correlation tomography system for three-dimensional blood flow imaging in a murine bone graft model.

Proctor, Ashley R (author): Department of Biomedical Engineering, University of Rochester

Hoffman, Michael D (author): Department of Biomedical Engineering, University of Rochester

Vella, Joseph B (author): Department of Biomedical Engineering, University of Rochester

Benoit, Danielle S W (author): Department of Biomedical Engineering, University of Rochester

Choe, Regine (author): Department of Biomedical Engineering, University of Rochester

(creator_code:org_t)

Related links:: http://www.ncbi.nlm....; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Abstract Subject headings

A non-contact galvanometer-based optical scanning system for diffuse correlation tomography was developed for monitoring bone graft healing in a murine femur model. A linear image reconstruction algorithm for diffuse correlation tomography was tested using finite-element method based simulated data and experimental data from a femur or a tube suspended in a homogeneous liquid phantom. Finally, the non-contact system was utilized to monitor in vivo blood flow changes prior to and one week after bone graft transplantation within murine femurs. Localized blood flow changes were observed in three mice, demonstrating a potential for quantification of longitudinal blood flow associated with bone graft healing.

By the author/editor: Han, Songfeng; Johansson, Johan ...; Mireles, Miguel; Proctor, Ashley ...; Hoffman, Michael ...; Vella, Joseph B; show more...; Benoit, Danielle ...; Durduran, Turgut; Choe, Regine; show less...

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Image Pr ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.