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Diffuse reflectance spectroscopy of the human tympanic membrane in otitis media
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- Sundberg, Mikael (author)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan
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- Peebo, Markus (author)
- Linköpings universitet,Oto-Rhino-Laryngologi,Hälsouniversitetet
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- Öberg, Åke (author)
- Linköpings universitet,Fysiologisk mätteknik,Tekniska högskolan
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- (creator_code:org_t)
- 2004-10-14
- 2004
- English.
- In: Physiological Measurement. - : IOP Publishing. - 0967-3334 .- 1361-6579. ; 25:6, s. 1473-1483
- Journal article (peer-reviewed)
Abstract
Subject headings
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- We have investigated if features in the diffuse reflectance spectra from in vivo spectroscopic measurements of the tympanic membrane could aid the diagnosis of otitis media in children. Diffuse reflectance spectroscopy, in the visible wavelength range, was used in 15 ears from children with otitis media with effusion before and after myringotomy and in 15 healthy ears as a reference. Two previously published erythema detection algorithms yielded numerical quantities of haemoglobin content. With a combination of the algorithms, induced erythema (after myringotomy) was distinguished from healthy ears using Student's t-test (p < 0.01). Otitis media with mucous effusion was distinguished from (1) otitis media with serous effusion, (2) induced erythema and (3) healthy ears, (p < 0.05) using Student's t-test for independent groups and the paired t-test for dependent groups. Our results imply that reflectance spectroscopy is a promising technique to be used for the diagnosis of otitis media.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Keyword
- diffuse reflectance spectroscopy
- otitis media
- tympanic membrane
- erythema
- Medical engineering
- Medicinsk teknik
Publication and Content Type
- ref (subject category)
- art (subject category)
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