Search: onr:"swepub:oai:DiVA.org:liu-130322" > Effects of a Psycho...
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000 | 05054naa a2200577 4500 | |
001 | oai:DiVA.org:liu-130322 | |
003 | SwePub | |
008 | 160728s2016 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:133800054 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1303222 URI |
024 | 7 | a https://doi.org/10.1159/0004453552 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1338000542 URI |
040 | a (SwePub)liud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Philipp Klein, Janu Medical University of Lubeck, Germany4 aut |
245 | 1 0 | a Effects of a Psychological Internet Intervention in the Treatment of Mild to Moderate Depressive Symptoms: Results of the EVIDENT Study, a Randomized Controlled Trial |
264 | c 2016-05-27 | |
264 | 1 | b KARGER,c 2016 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|German Federal Ministry of Health [II A 5-2512 FSB 052] | |
520 | a Background: Mild to moderate depressive symptoms are common but often remain unrecognized and treated inadequately. We hypothesized that an Internet intervention in addition to usual care is superior to care as usual alone (CAU) in the treatment of mild to moderate depressive symptoms in adults. Methods: This trial was controlled, randomized and assessor-blinded. Participants with mild to moderate depressive symptoms (Patient Health Questionnaire, PHQ-9, score 5-14) were recruited from clinical and non-clinical set-tings and randomized to either CAU or a 12-week Internet intervention (Deprexis) adjunctive to usual care. Outcomes were assessed at baseline, 3 months (post-assessment) and 6 months (follow-up). The primary outcome measure was self-rated depression severity (PHQ-9). The main analysis was based on the intention-to-treat principle and used linear mixed models. Results: A total of 1,013 participants were randomized. Changes in PHQ-9 from baseline differed significantly between groups (t(825) = 6.12, p amp;lt; 0.001 for the main effect of group). The post-assessment between-group effect size in favour of the intervention was d = 0.39 (95% CI: 0.13-0.64). It was stable at follow-up, with d = 0.32 (95% CI: 0.06-0.69). The rate of participants experiencing at least minimally clinically important PHQ-9 change at the post-assessment was higher in the intervention group (35.6 vs. 20.2%) with a number needed to treat of 7 (95% CI: 5-10). Conclusions: The Internet intervention examined in this trial was superior to CAU alone in reducing mild to moderate depressive symptoms. The magnitude of the effect is clinically important and has public health implications. (C) 2016 S. Karger AG, Basel | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
653 | a Internet intervention; Cognitive behaviour therapy; Depression; Randomized controlled trial | |
700 | 1 | a Berger, Thomasu University of Bern, Switzerland4 aut |
700 | 1 | a Schroeder, Johannau University of Medical Centre Hamburg Eppendorf, Germany4 aut |
700 | 1 | a Spaeth, Christinau Medical University of Lubeck, Germany4 aut |
700 | 1 | a Meyer, Bjoernu GAIA AG, Germany; City University of London, England4 aut |
700 | 1 | a Caspar, Franzu University of Bern, Switzerland4 aut |
700 | 1 | a Lutz, Wolfgangu University of Trier, Germany4 aut |
700 | 1 | a Arndt, Aliceu University of Trier, Germany4 aut |
700 | 1 | a Greiner, Wolfgangu University of Bielefeld, Germany4 aut |
700 | 1 | a Graefe, Violau University of Bielefeld, Germany4 aut |
700 | 1 | a Hautzinger, Martinu University of Tubingen, Germany4 aut |
700 | 1 | a Fuhr, Kristinau University of Tubingen, Germany4 aut |
700 | 1 | a Rose, Matthiasu Charite, Germany; University of Massachusetts, MA 01605 USA4 aut |
700 | 1 | a Nolte, Sandrau Charite, Germany; Deakin University, Australia4 aut |
700 | 1 | a Loewe, Berndu University of Medical Centre Hamburg Eppendorf, Germany4 aut |
700 | 1 | a Andersson, Gerhardu Karolinska Institutet,Linköpings universitet,Psykologi,Filosofiska fakulteten,Karolinska Institute, Sweden4 aut0 (Swepub:liu)geran87 |
700 | 1 | a Vettorazzi, Eiku University of Medical Centre Hamburg Eppendorf, Germany4 aut |
700 | 1 | a Moritz, Steffenu University of Medical Centre Hamburg Eppendorf, Germany4 aut |
700 | 1 | a Hohagen, Fritzu Medical University of Lubeck, Germany4 aut |
710 | 2 | a Medical University of Lubeck, Germanyb University of Bern, Switzerland4 org |
773 | 0 | t Psychotherapy and Psychosomaticsd : KARGERg 85:4, s. 218-228q 85:4<218-228x 0033-3190x 1423-0348 |
856 | 4 | u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117387 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130322 |
856 | 4 8 | u https://doi.org/10.1159/000445355 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:133800054 |
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