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- Cedersund, Gunnar,1978-Linköpings universitet,Institutionen för medicinsk teknik,Institutionen för klinisk och experimentell medicin,Tekniska fakulteten,Integrative Systems Biology (author)
Optimization in biology parameter estimation and the associated optimization problem
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- 2015-10-27
- Cham :Springer,2016
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:liu-130997
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130997URI
- https://doi.org/10.1007/978-3-319-21296-8_7DOI
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- Language:English
- Summary in:English
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Notes
- Parameter estimation – the assignment of values to the parameters in a model – is an important and time-consuming task in computational biology. Recent computational and algorithmic developments have provided novel tools to improve this estimation step. One of these improvements concerns the optimization step, where the parameter space is explored to find interesting regions. In this chapter we review the parameter estimation problem, with a special emphasis on the associated optimization methods. In relation to this, we also provide concepts and tools to help you select the appropriate methodology for a specific scenario.
Subject headings and genre
- TEKNIK OCH TEKNOLOGIER Elektroteknik och elektronik Reglerteknik hsv//swe
- ENGINEERING AND TECHNOLOGY Electrical Engineering, Electronic Engineering, Information Engineering Control Engineering hsv//eng
- Parameter estimation
- Optimization
- Heuristic
- Fitness function
Added entries (persons, corporate bodies, meetings, titles ...)
- Samuelsson, OscarUppsala universitet (author)
- Ball, GordonKarolinska institutet, Stockholm (author)
- Tegnér, JesperUnit of Computational Medicine, Department of Medicine, Karolinska Institutet, Solna, Sweden (author)
- Gomez-Cabrero, DavidKarolinska institutet, Stockholm (author)
- Linköpings universitetInstitutionen för medicinsk teknik (creator_code:org_t)
Related titles
- In:Uncertainty in biologyCham : Springer, s. 177-19797833192129519783319212968
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- http://libris.kb.se/bib/5jhsvfcf34ql711c
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130997
- https://doi.org/10.1007/978-3-319-21296-8_7
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