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Use of computed tom...
Use of computed tomography assessed kidney length to predict split renal GFR in living kidney donors
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- Gaillard, Francois (author)
- Paris Descartes University, France
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- Pavlov, Patrik (author)
- Linköpings universitet
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- Tissier, Anne-Marie (author)
- Paris Descartes University, France
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- Harache, Benoit (author)
- Paris Descartes University, France
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- Eladari, Dominique (author)
- Paris Descartes University, France; INSERM, France
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- Timsit, Marc-Olivier (author)
- Paris Descartes University, France
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- Fournier, Catherine (author)
- Paris Descartes University, France
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- Leon, Carine (author)
- Paris Descartes University, France
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- Hignette, Chantal (author)
- Paris Descartes University, France
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- Friedlander, Gerard (author)
- Paris Descartes University, France; INSERM, France
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- Correas, Jean-Michel (author)
- Paris Descartes University, France
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- Weinmann, Pierre (author)
- Paris Descartes University, France
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- Mejean, Arnaud (author)
- Paris Descartes University, France
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- Houillier, Pascal (author)
- Paris Descartes University, France; CNRS, France
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- Legendre, Christophe (author)
- Paris Descartes University, France
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- Courbebaisse, Marie (author)
- Paris Descartes University, France; INSERM, France
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(creator_code:org_t)
- 2016-05-24
- 2017
- English.
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In: European Radiology. - : SPRINGER. - 0938-7994 .- 1432-1084. ; 27:2, s. 651-659
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Screening of living kidney donors may require scintigraphy to split glomerular filtration rate (GFR). To determine the usefulness of computed tomography (CT) to split GFR, we compared scintigraphy-split GFR to CT-split GFR. We evaluated CT-split GFR as a screening test to detect scintigraphy-split GFR lower than 40 mL/min/1.73 m(2)/kidney. This was a monocentric retrospective study on 346 potential living donors who had GFR measurement, renal scintigraphy, and CT. We predicted GFR for each kidney by splitting GFR using the following formula: Volume-split GFR for a given kidney = measured GFR*[volume of this kidney/(volume of this kidney + volume of the opposite kidney)]. The same formula was used for length-split GFR. We compared length- and volume-split GFR to scintigraphy-split GFR at donation and with a 4-year follow-up. A better correlation was observed between length-split GFR and scintigraphy-split GFR (r = 0.92) than between volume-split GFR and scintigraphy-split GFR (r = 0.89). A length-split GFR threshold of 45 mL/min/1.73 m(2)/kidney had a sensitivity of 100 % and a specificity of 75 % to detect scintigraphy-split GFR less than 40 mL/min/1.73 m(2)/kidney. Both techniques with their respective thresholds detected living donors with similar eGFR evolution during follow-up. Length-split GFR can be used to detect patients requiring scintigraphy. aEuro cent Excellent correlation between kidney length and scintigraphy predicted GFR aEuro cent Kidney length screening detects all donors with GFR lower than 40 mL/min/1.73 m (2) aEuro cent Kidney length screening can replace scintigraphy screening.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- living donor; kidney; renal transplantation; CT; split renal function/split GFR
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Gaillard, Franco ...
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Pavlov, Patrik
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Tissier, Anne-Ma ...
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Harache, Benoit
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Eladari, Dominiq ...
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Timsit, Marc-Oli ...
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show more...
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Fournier, Cather ...
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Leon, Carine
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Hignette, Chanta ...
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Friedlander, Ger ...
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Correas, Jean-Mi ...
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Weinmann, Pierre
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Mejean, Arnaud
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Houillier, Pasca ...
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Legendre, Christ ...
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Courbebaisse, Ma ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Radiology Nuclea ...
- Articles in the publication
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European Radiolo ...
- By the university
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Linköping University