Clinical feasibility of 3D-QALAS - Single breath-hold 3D myocardial T1 and T2-mapping

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: onr:"swepub:oai:DiVA.org:liu-136856" > Clinical feasibilit...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Kvernby, SofiaLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV (author)

Clinical feasibility of 3D-QALAS - Single breath-hold 3D myocardial T1 and T2-mapping

Article/chapterEnglish2017

Publisher, publication year, extent ...

ELSEVIER SCIENCE INC,2017
electronicrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:liu-136856
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-136856URI
https://doi.org/10.1016/j.mri.2016.12.014DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Funding Agencies|Swedish Heart-Lung Foundation [20120449, 20140398]; Swedish Research Council [2014-6191]
Purpose: To investigate the in-vivo precision and clinical feasibility of 3D-QALAS- a novel method for simultaneous three-dimensional myocardial T1- and T2-mapping. Methods: Ten healthy subjects and 23 patients with different cardiac pathologies underwent cardiovascular 3 T MRI examinations including 3D-QALAS, MOLLI and T2-GraSE acquisitions. Precision was investigated in the healthy subjects between independent scans, between dependent scans and as standard deviation of consecutive scans. Clinical feasibility of 3D-QALAS was investigated for native and contrast enhanced myocardium in patients. Data were analyzed using mean value and 95% confidence interval, Pearson correlation, Paired t-tests, intraclass correlation and Bland-Altman analysis. Results: Average myocardial relaxation time values and SD from eight repeated acquisitions within the group of healthy subjects were 1178 +/- 18.5 ms (1.6%) for T1 with 3D-QALAS, 52.7 +/- 1.2 ms (23%) for T2 with 3D-QALAS, 1145 +/- 10.0 ms (0.9%) for Tl with MOLLI and 49.2 +/- 0.8 ms (1.6%) for T2 with GraSE. Myocardial Tl and T2 relaxation times obtained with 3D-QALAS correlated very well with reference methods; MOW for T1 (r = 0.994) and T2-GraSE for T2 (r = 0.818) in the 23 patients. Average native/post-contrast myocardial Tl values from the patients were 1166.2 ms/411.8 ms for 3D-QALAS and 1174.4 ms/438.9 ms for MOW. Average native myocardial T2 values from the patients were 53.2 ms for 3D-QAIAS and 54.4 ms for T2-GraSE. Conclusions: Repeated independent and dependent scans together with the intra-scan repeatability, demonstrated all a very good precision for the 3D-QALAS method in healthy volunteers. This study shows that 3D T1 and T2 mapping in the left ventricle is feasible in one breath hold for patients with different cardiac pathologies using 3D-QALAS. (C) 2016 Elsevier Inc. All rights reserved.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
T1 mapping; T2 mapping; Myocardium; Precision; 3D-QALAS; Validation

Added entries (persons, corporate bodies, meetings, titles ...)

Warntjes, Marcel Jan BertusLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US,SyntheticMR AB, Linkoping, Sweden(Swepub:liu)marwa64 (author)
Engvall, JanLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US(Swepub:liu)janen74 (author)
Carlhäll, CarljohanLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US(Swepub:liu)carca13 (author)
Ebbers, TinoLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US(Swepub:liu)tineb49 (author)
Linköpings universitetAvdelningen för kardiovaskulär medicin (creator_code:org_t)

Related titles

In:Magnetic Resonance Imaging: ELSEVIER SCIENCE INC38, s. 13-200730-725X1873-5894

Internet link

Find in a library

Magnetic Resonance Imaging (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Kvernby, Sofia; Warntjes, Marcel ...; Engvall, Jan; Carlhäll, Carljo ...; Ebbers, Tino

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

Articles in the publication: Magnetic Resonan ...

By the university: Linköping University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se