Search: onr:"swepub:oai:DiVA.org:liu-13830" >
Early diabetic comp...
Early diabetic complications in a population of young patients with Type 1 diabetes mellitus despite intensive treatment
-
- Nordwall, Maria (author)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
-
- Hyllienmark, Lars (author)
- Karolinska Institutet,Linköpings universitet,Klinisk Neurofysiologi,Hälsouniversitetet
-
- Ludvigsson, Johnny (author)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
-
(creator_code:org_t)
- Walter de Gruyter GmbH, 2006
- 2006
- English.
-
In: Journal of Pediatric Endocrinology & Metabolism. - : Walter de Gruyter GmbH. - 0334-018X .- 2191-0251. ; 19:1, s. 45-54
- Related links:
-
http://cat.inist.fr/...
-
show more...
-
http://urn.kb.se/res...
-
https://urn.kb.se/re...
-
http://kipublication...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Aim: To describe the prevalence of early complications in an unselected population of patients with type 1 diabetes mellitus (DM1) diagnosed in childhood with intensive insulin treatment from diagnosis.Methods: Eighty children and adolescents with DM1, age 7-22 years and DM1 duration >3 years, were studied. Neuropathy was defined as abnormal nerve conduction finding in ≥2 of 4 nerves (sural and peroneal nerves), nephropathy as albumin excretion rate ≥20 μg/min and retinopathy as all grades of retinal changes in fundus photographs.Results: The prevalence of neuropathy was 59%, of retinopathy 27% and of nephropathy 5% after 13 years DM1 duration. Mean (SD) long-term HbA1c was 8.4 (0.9)% (DCCT-corrected value).Conclusion: Even in a population with intensive insulin treatment from the beginning and fairly good metabolic control, the prevalence of subclinical neuropathy was high, while other diabetic complications were lower than usually reported.
Keyword
- type 1 diabetes mellitus ; diabetic nephropathy ; diabetic neuropathy ; diabetic retinopathy ; prevalence
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database