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Precision of MRI-ba...
Precision of MRI-based body composition measurements of postmenopausal women
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- West, Janne, 1982- (author)
- Linköpings universitet,Avdelningen för radiologiska vetenskaper,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Medicinska fakulteten
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- Romu, Thobias (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Tekniska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Adv MR Analyt AB, Linkoping, Sweden
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- Thorell, Sofia (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Institutionen för medicin och hälsa,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV
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- Lindblom, Hanna (author)
- Linköpings universitet,Avdelningen för fysioterapi,Medicinska fakulteten
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- Berin, Emilia (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten
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- Spetz Holm, Anna-Clara (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, Kvinnokliniken US
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- Lindh Åstrand, Lotta (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, Kvinnokliniken US
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- Karlsson, Anette (author)
- Linköpings universitet,Avdelningen för medicinsk teknik,Tekniska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV
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- Borga, Magnus (author)
- Linköpings universitet,Avdelningen för medicinsk teknik,Tekniska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Adv MR Analyt AB, Linkoping, Sweden
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- Hammar, Mats (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, Kvinnokliniken US
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- Dahlqvist Leinhard, Olof, 1978- (author)
- Linköpings universitet,Avdelningen för radiologiska vetenskaper,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Radiofysikavdelningen US,Adv MR Analyt AB, Linkoping, Sweden
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(creator_code:org_t)
- 2018-02-07
- 2018
- English.
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In: PLOS ONE. - San Francisco, United States : Public Library of Science. - 1932-6203. ; 13:2
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Abstract
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- Objectives To determine precision of magnetic resonance imaging (MRI) based fat and muscle quantification in a group of postmenopausal women. Furthermore, to extend the method to individual muscles relevant to upper-body exercise. Materials and methods This was a sub-study to a randomized control trial investigating effects of resistance training to decrease hot flushes in postmenopausal women. Thirty-six women were included, mean age 56 +/- 6 years. Each subject was scanned twice with a 3.0T MR-scanner using a whole-body Dixon protocol. Water and fat images were calculated using a 6-peak lipid model including R2*-correction. Body composition analyses were performed to measure visceral and subcutaneous fat volumes, lean volumes and muscle fat infiltration (MFI) of the muscle groups thigh muscles, lower leg muscles, and abdominal muscles, as well as the three individual muscles pectoralis, latissimus, and rhomboideus. Analysis was performed using a multi-atlas, calibrated water-fat separated quantification method. Liver-fat was measured as average proton density fat-fraction (PDFF) of three regions-of-interest. Precision was determined with Bland-Altman analysis, repeatability, and coefficient of variation. Results All of the 36 included women were successfully scanned and analysed. The coefficient of variation was 1.1% to 1.5% for abdominal fat compartments (visceral and subcutaneous), 0.8% to 1.9% for volumes of muscle groups (thigh, lower leg, and abdomen), and 2.3% to 7.0% for individual muscle volumes (pectoralis, latissimus, and rhomboideus). Limits of agreement for MFI was within +/- 2.06% for muscle groups and within +/- 5.13% for individual muscles. The limits of agreement for liver PDFF was within +/- 1.9%. Conclusion Whole-body Dixon MRI could characterize a range of different fat and muscle compartments with high precision, including individual muscles, in the study-group of postmenopausal women. The inclusion of individual muscles, calculated from the same scan, enables analysis for specific intervention programs and studies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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West, Janne, 198 ...
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Romu, Thobias
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Thorell, Sofia
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Lindblom, Hanna
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Berin, Emilia
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Spetz Holm, Anna ...
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Lindh Åstrand, L ...
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Karlsson, Anette
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Borga, Magnus
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Hammar, Mats
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Dahlqvist Leinha ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Sport and Fitnes ...
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PLOS ONE
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Linköping University