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Intermittent Access...
Intermittent Access to Ethanol Induces Escalated Alcohol Consumption in Primates
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- Lindell, S. G. (author)
- Laboratory of Comparative Behavioral Genomics, NIH/NIAAA/LNG, USA; Laboratory of Clinical and Translational Studies, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, USA
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- Schwandt, M. L. (author)
- Laboratory of Clinical and Translational Studies, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, USA
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- Suomi, S. J. (author)
- Laboratory of Comparative Ethology, National Institutes of Health/National Institute of Child Health and Human Development, NIH Animal Center, USA
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- Rice, K. C. (author)
- Chemical Biology Research Branch, National Institute on Drug Abuse, Bethesda, USA
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- Heilig, Markus, 1959- (author)
- Linköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten,Region Östergötland, Psykiatriska kliniken,Laboratory of Clinical and Translational Studies, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, USA
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- Barr, C. S. (author)
- Laboratory of Comparative Behavioral Genomics, NIH/NIAAA/LNG, USA; Laboratory of Clinical and Translational Studies, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, USA
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(creator_code:org_t)
- 2017
- 2017
- English.
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In: Journal of addictive behaviors, therapy and rehabilitation. - : SciTechnol. - 2324-9005. ; 6:1
- Related links:
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https://liu.diva-por... (primary) (Raw object)
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http://liu.diva-port...
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https://urn.kb.se/re...
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https://doi.org/10.4...
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Abstract
Subject headings
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- Escalation of voluntary alcohol drinking is characteristic of alcohol addiction and can be induced in rodents using intermittent access to alcohol. This model has been used to evaluate candidate therapeutics, but key systems involved in the transition into alcohol addiction, such as CRF, differ in their organization between rodents and primates. We examined the ability of an intermittent access schedule to induce escalation of voluntary alcohol drinking in non-human primates and used this model to assess the role of corticotropin releasing hormone (CRF) signaling in this process.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Beroendelära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Substance Abuse (hsv//eng)
Keyword
- Alcohol; CRF; Dependence; Intermittent access; Rhesus macaque
Publication and Content Type
- ref (subject category)
- art (subject category)
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