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Inflammation och at...
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Jonasson, Lena,1956-Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
(author)
Inflammation och ateroskleros – sista pusselbiten är på plats : Inflammation är en aktör vid ateroskleros: nya fynd kan ge ny måltavla för effektiv läkemedelsterapi
- Article/chapterEnglish2017
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Stockholm, Sweden :Läkartidningen Förlag AB,2017
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LIBRIS-ID:oai:DiVA.org:liu-146333
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-146333URI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Inflammation and atherosclerosis - last piece of the puzzle has fallen into place Inflammation is a major component of atherosclerotic lesions and inflammatory biomarkers can be used to predict cardiovascular disease. Still, it has been unclear whether inflammation is a driving force in atherosclerosis, or merely an epiphenomenon. The recently published results of the CANTOS trial shows that treatment with canacinumab, a monoclonal antibody to the proinflammatory cytokine interleukin-1ß, led to a significantly lower rate of recurrent cardiovascular events, compared to placebo. Thus, it establishes beyond doubt that inflammation is a treatable pathogenetic mechanism in atherosclerosis.
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Hansson, GöranKarolinska Institutet Department of Medicine Solna - Stockholm, Sweden Karolinska Institutet Department of Medicine Solna - Stockholm, Sweden
(author)
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Linköpings universitetAvdelningen för kardiovaskulär medicin
(creator_code:org_t)
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In:LäkartidningenStockholm, Sweden : Läkartidningen Förlag AB1140023-72051652-7518
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