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Evaluation of a hig...
Evaluation of a high framerate multi-exposure laser speckle contrast imaging setup
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- Hultman, Martin, 1992- (author)
- Linköpings universitet,Avdelningen för medicinsk teknik,Tekniska fakulteten
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- Fredriksson, Ingemar, 1980- (author)
- Linköpings universitet,Avdelningen för medicinsk teknik,Tekniska fakulteten,Perimed AB, Järfälla-Stockholm, Sweden
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- Strömberg, Tomas, 1966- (author)
- Linköpings universitet,Avdelningen för medicinsk teknik,Tekniska fakulteten
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- Larsson, Marcus, 1974- (author)
- Linköpings universitet,Avdelningen för medicinsk teknik,Tekniska fakulteten
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(creator_code:org_t)
- SPIE - International Society for Optical Engineering, 2018
- 2018
- English.
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In: High-Speed Biomedical Imaging and Spectroscopy III. - : SPIE - International Society for Optical Engineering. - 9781510614963
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https://liu.diva-por... (primary) (Raw object)
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http://liu.diva-port...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- We present a first evaluation of a new multi-exposure laser speckle contrast imaging (MELSCI) system for assessing spatial variations in the microcirculatory perfusion. The MELSCI system is based on a 1000 frames per second 1-megapixel camera connected to a field programmable gate arrays (FPGA) capable of producing MELSCI data in realtime. The imaging system is evaluated against a single point laser Doppler flowmetry (LDF) system during occlusionrelease provocations of the arm in five subjects. Perfusion is calculated from MELSCI data using current state-of-the-art inverse models. The analysis displayed a good agreement between measured and modeled data, with an average error below 6%. This strongly indicates that the applied model is capable of accurately describing the MELSCI data and that the acquired data is of high quality. Comparing readings from the occlusion-release provocation showed that the MELSCI perfusion was significantly correlated (R=0.83) to the single point LDF perfusion, clearly outperforming perfusion estimations based on a single exposure time. We conclude that the MELSCI system provides blood flow images of enhanced quality, taking us one step closer to a system that accurately can monitor dynamic changes in skin perfusion over a large area in real-time
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering (hsv//eng)
Publication and Content Type
- ref (subject category)
- kon (subject category)
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