Evaluation of clinical outcomes following implantation of a sub-2-mm hydrophilic acrylic MICS intraocular lens

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Dick, H BurkhardUniversity Eye Hospital Bochum, Bochum, Germany (author)

Evaluation of clinical outcomes following implantation of a sub-2-mm hydrophilic acrylic MICS intraocular lens

Article/chapterEnglish2019

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2018-04-13
Springer Netherlands,2019
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LIBRIS-ID:oai:DiVA.org:liu-153462
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-153462URI
https://doi.org/10.1007/s10792-018-0905-3DOI

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Language:English
Summary in:English

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PURPOSE: To evaluate clinical outcomes following sub-2-mm microincision cataract surgery (MICS) and intraocular lens (IOL) implantation.SETTING: Five EU clinical sites.DESIGN: Prospective, multicenter, open-label, single-arm, non-randomized.METHODS: Preoperative assessment involved visual acuity (VA), intraocular pressure and biometry measurements. 1.4-mm wound-assisted or 1.8-mm MICS was performed. Follow-up visits were made 1 day, 1-2 weeks, 1-2 and 4-6 months after surgery. The incision size, corrected distance VA (CDVA), uncorrected distance VA, manifest refraction spherical equivalent (MRSE), refraction predictability/stability and IOL decentration were assessed. At 12-, 18-, and 24-month, long-term centration, posterior capsular opacification (PCO) and Nd:YAG capsulotomy rates were investigated.RESULTS: A total of 103 eyes were implanted with the study IOL (INCISE, Bausch & Lomb), 96 of which were included in visual outcome analysis. A mean 6-month CDVA of - 0.02 logMAR (20/20 + 1) was observed and 75 eyes (79.8%) and 93 eyes (98.3%) achieved a visual acuity of at least 20/20 or 20/40. Mean MRSE was - 0.20 ± 0.60 D. Mean absolute predictive error was 0.44 ± 0.36 D, with 90.4% within 1.00 D of target. Mean total decentration was 0.35 ± 0.36 mm at 6 months and 0.32 ± 0.14 mm at 24 months (p > 0.05). 24-month evaluation of posterior capsular opacification score was 0.03 for the central area. A Nd:YAG rate of 3.4% was observed at 24 months.CONCLUSIONS: The new MICS IOL provided excellent visual outcomes and was safe and effective for the sub-2-mm procedure. The MICS IOL demonstrated long-term centration, stability and a low rate of PCO development.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Oftalmologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Ophthalmology hsv//eng
Implantation
Intraocular lens
Microincision cataract surgery

Added entries (persons, corporate bodies, meetings, titles ...)

Schultz, TimUniversity Eye Hospital Bochum, Bochum, Germany (author)
Lesieur, GillesCentre Ophtalmologique Iridis, Albi, France (author)
Morselli, SimonettaOspedale di Bassano del Grappa Bassano del Grappa, Bassano del Grappa, Italy (author)
Toso, AntonioOspedale di Bassano del Grappa Bassano del Grappa, Bassano del Grappa, Italy (author)
Alio, Jorge LVissum-Instituto Oftalmologico de Alicante, University Miguel Hernandez, Alicante, Spain (author)
Buckhurst, Phillip JSchool of Health Professions, Plymouth University, Plymouth, UK (author)
Johansson, Björn,1958-Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Region Östergötland, Ögonkliniken US,St. Erik Eye Hospital, Stockholm, Sweden(Swepub:liu)bjojo58 (author)
University Eye Hospital Bochum, Bochum, GermanyCentre Ophtalmologique Iridis, Albi, France (creator_code:org_t)

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In:International ophtalmology: Springer Netherlands39:5, s. 1043-10540165-57011573-2630

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By the author/editor: Dick, H Burkhard; Schultz, Tim; Lesieur, Gilles; Morselli, Simone ...; Toso, Antonio; Alio, Jorge L; show more...; Buckhurst, Phill ...; Johansson, Björn ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Ophthalmology

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