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Characterization of...
Characterization of extended-spectrum -lactamase-producing Escherichia coli harboring mcr-1 and toxin genes from human fecal samples from China
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- Berglund, Björn (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten
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- Chen, Baoli (author)
- Shandong Ctr Dis Control and Prevent, Peoples R China
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- Tärnberg, Maria (author)
- Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten
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- Sun, Qiang (author)
- Shandong Univ, Peoples R China
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- Xu, Liuchen (author)
- Shandong Ctr Dis Control and Prevent, Peoples R China
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- Welander, Jenny (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten,Region Östergötland, Klinisk mikrobiologi
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- Li, Yan (author)
- Shandong Ctr Dis Control and Prevent, Peoples R China
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- Bi, Zhenwang (author)
- Shandong Ctr Dis Control and Prevent, Peoples R China
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- Nilsson, Maud (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten
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- Nilsson, Lennart E (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten
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(creator_code:org_t)
- FUTURE MEDICINE LTD, 2018
- 2018
- English.
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In: Future Microbiology. - : FUTURE MEDICINE LTD. - 1746-0913 .- 1746-0921. ; 13:15, s. 1647-1656
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Subject headings
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- Aim: To characterize extended-spectrum -lactamase-producing Escherichia coli harboring the colistin resistance gene mcr-1 from human fecal samples collected in 2012 in a rural area of Shandong province, PR China. Materials amp; methods: Whole-genome sequencing and antimicrobial susceptibility testing was performed on 25 mcr-1-positive isolates to determine carriage of antibiotic resistance and virulence genes, diversity and antibiotic resistance profiles. Results: The isolates were highly genetically diverse and carried a large variety of different antibiotic resistance genes. The multidrug-resistance rate was high (96%). Virulence genes associated with intestinal pathogenic E. coli were carried by 32% of the isolates. Conclusion: Further monitoring of the epidemiological situation is necessary to ensure a preparedness for potential emergence of novel, difficult-to-treat strains and awareness of available treatment options.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- antibiotic resistance; colistin; ESBL; Escherichia coli; intestinal pathogenic E; coli; mcr-1; whole-genome sequencing
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Berglund, Björn
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Chen, Baoli
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Tärnberg, Maria
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Sun, Qiang
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Xu, Liuchen
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Welander, Jenny
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show more...
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Li, Yan
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Bi, Zhenwang
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Nilsson, Maud
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Nilsson, Lennart ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Microbiology in ...
- Articles in the publication
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Future Microbiol ...
- By the university
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Linköping University