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Conjugated Oligo- a...
Conjugated Oligo- and Polymers for Bacterial Sensing
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- Loffler, Susanne (author)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Antypas, Hails (author)
- Karolinska Inst, Sweden
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- Choong, Ferdinand X. (author)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Nilsson, Peter (author)
- Linköpings universitet,Kemi,Tekniska fakulteten
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- Richter-Dahlfors, Agneta (author)
- Karolinska Institutet,Karolinska Inst, Sweden
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(creator_code:org_t)
- 2019-04-18
- 2019
- English.
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In: Frontiers in Chemistry. - : FRONTIERS MEDIA SA. - 2296-2646. ; 7
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Abstract
Subject headings
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- Fast and accurate detection of bacteria and differentiation between pathogenic and commensal colonization are important keys in preventing the emergence and spread of bacterial resistance toward antibiotics. As bacteria undergo major lifestyle changes during colonization, bacterial sensing needs to be achieved on different levels. In this review, we describe how conjugated oligo- and polymers are used to detect bacterial colonization. We summarize how oligothiophene derivatives have been tailor-made for detection of biopolymers produced by a wide range of bacteria upon entering the biofilm lifestyle. We further describe how these findings are translated into diagnostic approaches for biofilm-related infections. Collectively, this provides an overview on how synthetic biorecognition elements can be used to produce fast and easy diagnostic tools and new methods for infection control.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- conjugated polymers; conjugated oligoelectrolytes; luminescent conjugated oligothiophenes; bacterial sensing; biofilms; curli; cellulose
Publication and Content Type
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