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A red- emissive mit...
A red- emissive mitochondrial probe for imaging of the viscosity in living cells
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- Wang, Hui (author)
- Wannan Med Coll, Peoples R China
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- Cai, Fengze (author)
- Wannan Med Coll, Peoples R China
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- Zhou, Le (author)
- Wannan Med Coll, Peoples R China
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- He, Jing (author)
- Wannan Med Coll, Peoples R China
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- Feng, Dexiang (author)
- Wannan Med Coll, Peoples R China
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- Wei, Yan (author)
- Wannan Med Coll, Peoples R China
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- Feng, Zhijun (author)
- Wannan Med Coll, Peoples R China
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- Gu, Xiaoxia (author)
- Wannan Med Coll, Peoples R China
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- Uvdal, Kajsa (author)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
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- Hu, Zhang-Jun (author)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
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(creator_code:org_t)
- 2019
- 2019
- English.
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In: New Journal of Chemistry. - : ROYAL SOC CHEMISTRY. - 1144-0546 .- 1369-9261. ; 43:22, s. 8811-8815
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A novel water- soluble fluorescent probe L based on indole salts has been designed, synthesized and fully characterized. The systematic investigations demonstrated that probe L shows red emission and the fluorescence intensity is linear with the viscosity of the medium. Probe L is able to selectively accumulate in mitochondria within 1 min without any additional reagents for membrane permeabilization. It has been used to distinguish the viscosity differences between mitochondria in normal and nystatin- treated HeLa cells. In addition, due to the good photostability, probe L can be used to monitor the dynamics of mitochondria. These results support that probe L might provide a promising approach for the fluorescence detection of mitochondrial viscosity in living biological systems.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Wang, Hui
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Cai, Fengze
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Zhou, Le
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He, Jing
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Feng, Dexiang
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Wei, Yan
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show more...
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Feng, Zhijun
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Gu, Xiaoxia
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Uvdal, Kajsa
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Hu, Zhang-Jun
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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and Organic Chemistr ...
- Articles in the publication
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New Journal of C ...
- By the university
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Linköping University