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Spinal signalling o...
Spinal signalling of C-fiber mediated pleasant touch in humans
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- Marshall, Andrew G. (author)
- Univ Liverpool, England; Liverpool John Moores Univ, England; Walton Ctr NHS Fdn Trust, England
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- Sharma, Manohar L. (author)
- Walton Ctr NHS Fdn Trust, England
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- Marley, Kate (author)
- Aintree Univ Hosp NHS Fdn Trust, England
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- Olausson, Håkan (author)
- Linköpings universitet,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Centrum för social och affektiv neurovetenskap,Region Östergötland, Neurofysiologiska kliniken US,Aintree Univ Hosp NHS Fdn Trust, England
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- McGlone, Francis P. (author)
- Liverpool John Moores Univ, England; Univ Liverpool, England
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(creator_code:org_t)
- ELIFE SCIENCES PUBLICATIONS LTD, 2019
- 2019
- English.
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In: eLIFE. - : ELIFE SCIENCES PUBLICATIONS LTD. - 2050-084X. ; 8
- Related links:
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.7...
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Abstract
Subject headings
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- C-tactile afferents form a distinct channel that encodes pleasant tactile stimulation. Prevailing views indicate they project, as with other unmyelinated afferents, in lamina I-spinothalamic pathways. However, we found that spinothalamic ablation in humans, whilst profoundly impairing pain, temperature and itch, had no effect on pleasant touch perception. Only discriminative touch deficits were seen. These findings preclude privileged C-tactile-lamina I-spinothalamic projections and imply integrated hedonic and discriminative spinal processing from the body.
Subject headings
- NATURVETENSKAP -- Biologi -- Biofysik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biophysics (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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