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No-touch saphenous ...
No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT): Rationale and design of a multicenter, prospective, registry-based randomized clinical trial
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- Ragnarsson, Sigurdur (author)
- Lund University,Lunds universitet,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Skåne University Hospital
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- Janiec, Mikael (author)
- Uppsala universitet,Thoraxkirurgi,Uppsala Univ Hosp, Sweden,Uppsala University Hospital
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- Modrau, Ivy Susanne (author)
- Aarhus Univ Hosp, Aarhus, Denmark.,Aarhus University Hospital, Aarhus, Denmark
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- Dreifaldt, Mats (author)
- Orebro Univ Hosp, Orebro, Sweden.,Örebro University Hospital, Örebro, Sweden,Uppsala University Hospital, Uppsala, Sweden,Uppsala Univ Hosp, Sweden
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- Ericsson, Anders (author)
- Blekinge Hosp, Karlskrona, Sweden.,Blekinge Hospital, Karlskrona, Sweden
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- Holmgren, Anders (author)
- Univ Hosp Umea, Umea, Sweden.,University Hospital of Umeå, Umeå, Sweden,Norrland University Hospital
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- Hultkvist, Henrik, 1968- (author)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland,Linköping University Hospital, Linköping, Sweden,Linkoping Univ Hosp, Linkoping, Sweden.
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- Jeppsson, Anders (author)
- Sahlgrens Univ Hosp, Gothenburg, Sweden.,Sahlgrenska University Hospital, Gothenburg, Sweden
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- Sartipy, Ulrik (author)
- Karolinska Institutet,Karolinska Univ Hosp, Sweden,Karolinska University Hospital
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- Ternstrom, Lisa (author)
- Sahlgrens Univ Hosp, Gothenburg, Sweden.,Sahlgrenska University Hospital, Gothenburg, Sweden
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- Vikholm, Per, 1985- (author)
- Uppsala universitet,Thoraxkirurgi
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- de Souza, Domingos Ramos, 1954- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Orebro Univ Hosp, Orebro, Sweden.,Örebro University Hospital
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- James, Stefan, 1964- (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala kliniska forskningscentrum (UCR),Uppsala Univ Hosp, Uppsala, Sweden.,Uppsala University Hospital
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- Thelin, Stefan (author)
- Uppsala universitet,Thoraxkirurgi,Uppsala Univ Hosp, Sweden,Uppsala University Hospital
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(creator_code:org_t)
- MOSBY-ELSEVIER, 2020
- 2020
- English.
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In: American Heart Journal. - : MOSBY-ELSEVIER. - 0002-8703 .- 1097-6744. ; 224, s. 17-24
- Related links:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Subject headings
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- The SWEDEGRAFT study (ClinicalTrials.gov Identifier: NCT03501303) tests the hypothesis that saphenous vein grafts (SVGs) harvested with the "no-touch" technique improves patency of coronary artery bypass grafts compared with the conventional open skeletonized technique. This article describes the rationale and design of the randomized trial and baseline characteristics of the population enrolled during the first 9 months of enrollment. The SWEDEGRAFT study is a prospective, binational multicenter, open-label, registry-based trial in patients undergoing first isolated nonemergent coronary artery bypass grafting (CABG), randomized 1:1 to no-touch or conventional open skeletonized vein harvesting technique, with a planned enrollment of 900 patients. The primary end point is the proportion of patients with graft failure defined as SVGs occluded or stenosed >50% on coronary computed tomography angiography at 2 years after CABG, earlier clinically driven coronary angiography demonstrating an occluded or stenosed >50% vein graft, or death within 2 years. High-quality health registries and coronary computed tomography angiography are used to assess the primary end point. The secondary end points include wound healing in the vein graft sites and the composite outcome of major adverse cardiac events during the first 2 years based on registry data. Demographics of the first 200 patients enrolled in the trial and other CABG patients operated in Sweden during the same time period are comparable when the exclusion criteria are taken into consideration.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Ragnarsson, Sigu ...
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Janiec, Mikael
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Modrau, Ivy Susa ...
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Dreifaldt, Mats
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Ericsson, Anders
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Holmgren, Anders
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show more...
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Hultkvist, Henri ...
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Jeppsson, Anders
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Sartipy, Ulrik
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Ternstrom, Lisa
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Vikholm, Per, 19 ...
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de Souza, Doming ...
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James, Stefan, 1 ...
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Thelin, Stefan
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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American Heart J ...
- By the university
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Linköping University
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Örebro University
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Uppsala University
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Karolinska Institutet
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Lund University