Search: onr:"swepub:oai:DiVA.org:liu-16959" >
Expresson of PTEN a...
-
Gauffin, FredrikaKarolinska Institutet,Karolinska University Hospital
(author)
Expresson of PTEN and SHP1, Ivestigated from Tissue Microarrays in Pediatric Acute Lymphoblastic, Leukemia
- Article/chapterEnglish2009
Publisher, publication year, extent ...
-
2009-07-09
-
Informa UK Limited,2009
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:liu-16959
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16959URI
-
https://doi.org/10.1080/08880010802625530DOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177647URI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:118293743URI
-
https://lup.lub.lu.se/record/1374842URI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-5329URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
PTEN and SHP1 are tumor suppressor genes involved in the regulation of cell cycle control and apoptosis. The authors investigated the protein expression of PTEN and SHP1, by immunohistochemistry in tissue microarrays from bone marrow samples in children, diagnosed with acute lymphoblastic leukaemia and nonmalignant controls. PTEN was overexpressed in diagnostic ALL samples, while SHP1 showed a low expression. Both proteins showed a significant difference in expression compared to nonmalignant controls. The roles of PTEN and SHP1 are not well investigated in pediatric leukemia and could in the future play a role as prognostic factors.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Diffner, EvaLund University,Lunds universitet,Patologi, Malmö,Forskargrupper vid Lunds universitet,Pathology, Malmö,Lund University Research Groups,Malmö University Hospital(Swepub:lu)med-evd
(author)
-
Gustafsson, BertilKarolinska Institutet,Östergötlands Läns Landsting,Linköpings universitet,Institutionen för klinisk och experimentell medicin,Hälsouniversitetet,Klinisk patologi och klinisk genetik(Swepub:liu)bergu52
(author)
-
Nordgren, AnnKarolinska Institutet,Karolinska Institute
(author)
-
Gjörloff Wingren, AnetteMalmö högskola,Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine,Malmö University Hospital,Fakulteten för hälsa och samhälle (HS)(Swepub:mau)hsangj
(author)
-
Sander, BirgittaKarolinska Institutet,Karolinska Institute
(author)
-
Persson, Jenny L.,ProfessorLund University,Lunds universitet,Patologi, Malmö,Forskargrupper vid Lunds universitet,Pathology, Malmö,Lund University Research Groups(Swepub:lu)medk-jpe
(author)
-
Gustafsson, BrittKarolinska Institute
(author)
-
Karolinska InstitutetKarolinska University Hospital
(creator_code:org_t)
Related titles
-
In:Pediatric Hematology & Oncology: Informa UK Limited26:1, s. 48-560888-00181521-0669
Internet link
Find in a library
To the university's database