Search: onr:"swepub:oai:DiVA.org:liu-175846" >
Antibiotic resistan...
Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010-2018
-
- Möller, Vidar (author)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland
-
- Östholm Balkhed, Åse (author)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland
-
- Berild, Dag (author)
- Oslo Univ Hosp, Norway; Univ Oslo, Norway
-
show more...
-
- Fredrikson, Mats (author)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten
-
- Gottfredsson, Magnus (author)
- Landspitali Univ Hosp, Iceland; Univ Iceland, Iceland
-
- Holmbom, Martin (author)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Urologiska kliniken i Östergötland
-
- Järvinen, Asko (author)
- Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
-
- Kristjansson, Mar (author)
- Landspitali Univ Hosp, Iceland; Univ Iceland, Iceland
-
- Rydell, Ulf (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet
-
- Sönksen, Ute Wolff (author)
- Statens Serum Inst, Denmark
-
- Kolmos, Hans Joern (author)
- Odense Univ Hosp, Denmark
-
- Hanberger, Håkan (author)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland
-
show less...
-
(creator_code:org_t)
- 2021-05-10
- 2021
- English.
-
In: Infectious Diseases. - : Taylor & Francis. - 2374-4235 .- 2374-4243. ; 53:8, s. 607-618
- Related links:
-
https://liu.diva-por... (primary) (Raw object)
-
show more...
-
https://www.tandfonl...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Background The Nordic countries have comparable nationwide antibiotic resistance surveillance systems and individual antibiotic stewardship programmes. The aim of this study was to assess antibiotic resistance among major pathogens in relation to practice guidelines for hospital antibiotic treatment and antibiotic use in Nordic countries 2010-2018. Methods Antibiotic resistance among invasive isolates from 2010-2018 and aggregated antibiotic use were obtained from the European Centre for Disease Prevention and Control. Hospital practice guidelines were obtained from national or regional guidelines. Results Antibiotic resistance levels among Escherichia coli and Klebsiella pneumoniae were similar in all Nordic countries in 2018 and low compared to the European mean. Guidelines for acute pyelonephritis varied; 2nd generation cephalosporin (Finland), 3rd generation cephalosporins (Sweden, Norway), ampicillin with an aminoglycoside or aminoglycoside monotherapy (Denmark, Iceland and Norway). Corresponding guidelines for sepsis of unknown origin were 2nd (Finland) or 3rd (Sweden, Norway, Iceland) generation cephalosporins, carbapenems, (Sweden) combinations of penicillin with an aminoglycoside (Norway, Denmark), or piperacillin-tazobactam (all Nordic countries). Methicillin-resistant Staphylococcus aureus rates were 0-2% and empirical treatment with anti-MRSA antibiotics was not recommended in any country. Rates of penicillin non-susceptibility among Streptococcus pneumoniae were low (<10%) except in Finland and Iceland (<15%), but benzylpenicillin was recommended for community-acquired pneumonia in all countries. Conclusion Despite similar resistance rates among Enterobacteriaceae there were differences in practice guidelines for pyelonephritis and sepsis. National surveillance of antibiotic resistance can be used for comparison and optimization of guidelines and stewardship interventions to preserve the low levels of antibiotic resistance in Nordic countries.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- Antibiotic resistance; practice guidelines as topic; antibiotic stewardship; Nordic countries
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Möller, Vidar
-
Östholm Balkhed, ...
-
Berild, Dag
-
Fredrikson, Mats
-
Gottfredsson, Ma ...
-
Holmbom, Martin
-
show more...
-
Järvinen, Asko
-
Kristjansson, Ma ...
-
Rydell, Ulf
-
Sönksen, Ute Wol ...
-
Kolmos, Hans Joe ...
-
Hanberger, Håkan
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Infectious Medic ...
- Articles in the publication
-
Infectious Disea ...
- By the university
-
Linköping University