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Autonomous Microcap...
Autonomous Microcapillary Drug Delivery System Self-Powered by a Flexible Energy Harvester
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- Gabrielsson, Erik (author)
- Linköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten
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- Jung, Young Hoon (author)
- Korea Adv Inst Sci & Technol KAIST, South Korea
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- Han, Jae Hyun (author)
- Korea Adv Inst Sci & Technol KAIST, South Korea
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- Joe, Daniel Juhyung (author)
- Korea Res Inst Stand & Sci KRISS, South Korea
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- Simon, Daniel (author)
- Linköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten
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- Lee, Keon Jae (author)
- Korea Adv Inst Sci & Technol KAIST, South Korea
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- Berggren, Magnus (author)
- Linköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten
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(creator_code:org_t)
- 2021-07-16
- 2021
- English.
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In: Advanced Materials Technologies. - : Wiley-Blackwell. - 2365-709X. ; 6:11
- Related links:
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https://liu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Implantable bioelectronic devices pave the way for novel biomedical applications operating at high spatiotemporal resolution, which is crucial for neural recording and stimulation, drug delivery, and brain-machine interfaces. Before successful long-term implantation and clinical applications, these devices face a number of challenges, such as mechanical and operational stability, biocompatibility, miniaturization, and powering. To address two of these crucial challenges-miniaturization and powering-the development and characterization of an electrophoretic drug delivery device, manufactured inside fused quartz fibers (outer diameter of 125 mu m), which is self-powered by a flexible piezoelectric energy harvester, are reported. The resulting device-the first integration of piezoelectric charging with "iontronic" delivery-exhibits a high delivery efficiency (number of neurotransmitters delivered per charges applied) and a direct correlation between the piezoelectric charging and the amount delivered (number of dynamic bends versus pmols delivered).
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Elektroteknik och elektronik -- Annan elektroteknik och elektronik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Electrical Engineering, Electronic Engineering, Information Engineering -- Other Electrical Engineering, Electronic Engineering, Information Engineering (hsv//eng)
Keyword
- bioelectronics; drug delivery; flexible energy harvester; microcapillary; organic electronics; self-powered
Publication and Content Type
- ref (subject category)
- art (subject category)
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