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  • Gabrielsson, ErikLinköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten (author)

Autonomous Microcapillary Drug Delivery System Self-Powered by a Flexible Energy Harvester

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2021-07-16
  • Wiley-Blackwell,2021
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-179966
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-179966URI
  • https://doi.org/10.1002/admt.202100526DOI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies|Swedish Foundation for Strategic ResearchSwedish Foundation for Strategic Research [IS14-0033, RIT15-0119]; National Research Foundation of KoreaNational Research Foundation of Korea [NRF-2017R1A2A1A18071765]; VinnovaVinnova [2016-04601]; Knut and Alice Wallenberg FoundationKnut & Alice Wallenberg Foundation; Onnesjo Foundation
  • Implantable bioelectronic devices pave the way for novel biomedical applications operating at high spatiotemporal resolution, which is crucial for neural recording and stimulation, drug delivery, and brain-machine interfaces. Before successful long-term implantation and clinical applications, these devices face a number of challenges, such as mechanical and operational stability, biocompatibility, miniaturization, and powering. To address two of these crucial challenges-miniaturization and powering-the development and characterization of an electrophoretic drug delivery device, manufactured inside fused quartz fibers (outer diameter of 125 mu m), which is self-powered by a flexible piezoelectric energy harvester, are reported. The resulting device-the first integration of piezoelectric charging with "iontronic" delivery-exhibits a high delivery efficiency (number of neurotransmitters delivered per charges applied) and a direct correlation between the piezoelectric charging and the amount delivered (number of dynamic bends versus pmols delivered).

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  • Jung, Young HoonKorea Adv Inst Sci & Technol KAIST, South Korea (author)
  • Han, Jae HyunKorea Adv Inst Sci & Technol KAIST, South Korea (author)
  • Joe, Daniel JuhyungKorea Res Inst Stand & Sci KRISS, South Korea (author)
  • Simon, DanielLinköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten(Swepub:liu)dansi08 (author)
  • Lee, Keon JaeKorea Adv Inst Sci & Technol KAIST, South Korea (author)
  • Berggren, MagnusLinköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten(Swepub:liu)magbe98 (author)
  • Linköpings universitetLaboratoriet för organisk elektronik (creator_code:org_t)

Related titles

  • In:Advanced Materials Technologies: Wiley-Blackwell6:112365-709X

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