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A descriptive study...
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Chew, MichelleLinköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, ANOPIVA US
(author)
A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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2021-10-03
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WILEY,2022
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:liu-180269
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-180269URI
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https://doi.org/10.1111/aas.13983DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agencies|NordForsk (Nordic COVID-19 Activities); Finnish Society of Intensive Care
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Background We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID-19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID-19 disease during the first wave of COVID-19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS-CoV-2, the ratio of requiring ICU admission for COVID-19 varied substantially (1.6%-6.7%). Apart from age (proportion of patients aged 65 years or over between 29% and 62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID-19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59%-85%) in all countries, the proportion of patients receiving renal replacement therapy (7%-26%) and various experimental therapies for COVID-19 disease varied substantially (e.g. use of hydroxychloroquine 0%-85%). Crude ICU mortality ranged from 11% to 33%. Conclusion There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID-19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention.
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Kattainen, SallaHelsinki Univ Hosp, Finland; Univ Helsinki, Finland
(author)
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Haase, NicolaiCopenhagen Univ Hosp, Denmark
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Buanes, Eirik A.Helse Bergen Hlth Trust, Norway
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Kristinsdottir, Linda B.Landspitali Natl Univ Hosp Iceland, Iceland
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Hofso, KristinOslo Univ Hosp, Norway; Lovisenberg Diaconal Univ Coll, Norway
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Laake, Jon HenrikOslo Univ Hosp, Norway; Oslo Univ Hosp, Norway
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Kvale, ReidarHelse Bergen HF, Norway; Haukeland Hosp, Norway
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Hastbacka, JohannaHelsinki Univ Hosp, Finland; Univ Helsinki, Finland
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Reinikainen, MattiUniv Eastern Finland, Finland; Kuopio Univ Hosp, Finland
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Bendel, StepaniUniv Eastern Finland, Finland; Kuopio Univ Hosp, Finland
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Varpula, TeroHelsinki Univ Hosp, Finland; Univ Helsinki, Finland
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Walther, StenLinköpings universitet,Medicinska fakulteten,Institutionen för hälsa, medicin och vård,Region Östergötland, Thorax-kärlkliniken i Östergötland,Varmland Cty Council, Sweden(Swepub:liu)stewa50
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Perner, AndersCopenhagen Univ Hosp, Denmark
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Flaatten, Hans K.Helse Bergen HF, Norway; Haukeland Hosp, Norway
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Sigurdsson, Martin ILandspitali Natl Univ Hosp Iceland, Iceland; Univ Iceland, Iceland
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Linköpings universitetAvdelningen för klinisk kemi och farmakologi
(creator_code:org_t)
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In:Acta Anaesthesiologica Scandinavica: WILEY66:1, s. 56-640001-51721399-6576
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Chew, Michelle
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Kattainen, Salla
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Haase, Nicolai
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Buanes, Eirik A.
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Kristinsdottir, ...
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Hofso, Kristin
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Laake, Jon Henri ...
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Kvale, Reidar
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Hastbacka, Johan ...
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Reinikainen, Mat ...
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Bendel, Stepani
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Varpula, Tero
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Walther, Sten
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Perner, Anders
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Flaatten, Hans K ...
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Sigurdsson, Mart ...
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