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A descriptive study...
A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries
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- Chew, Michelle (author)
- Linköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, ANOPIVA US
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- Kattainen, Salla (author)
- Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
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- Haase, Nicolai (author)
- Copenhagen Univ Hosp, Denmark
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- Buanes, Eirik A. (author)
- Helse Bergen Hlth Trust, Norway
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- Kristinsdottir, Linda B. (author)
- Landspitali Natl Univ Hosp Iceland, Iceland
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- Hofso, Kristin (author)
- Oslo Univ Hosp, Norway; Lovisenberg Diaconal Univ Coll, Norway
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- Laake, Jon Henrik (author)
- Oslo Univ Hosp, Norway; Oslo Univ Hosp, Norway
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- Kvale, Reidar (author)
- Helse Bergen HF, Norway; Haukeland Hosp, Norway
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- Hastbacka, Johanna (author)
- Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
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- Reinikainen, Matti (author)
- Univ Eastern Finland, Finland; Kuopio Univ Hosp, Finland
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- Bendel, Stepani (author)
- Univ Eastern Finland, Finland; Kuopio Univ Hosp, Finland
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- Varpula, Tero (author)
- Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
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- Walther, Sten (author)
- Linköpings universitet,Medicinska fakulteten,Institutionen för hälsa, medicin och vård,Region Östergötland, Thorax-kärlkliniken i Östergötland,Varmland Cty Council, Sweden
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- Perner, Anders (author)
- Copenhagen Univ Hosp, Denmark
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- Flaatten, Hans K. (author)
- Helse Bergen HF, Norway; Haukeland Hosp, Norway
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- Sigurdsson, Martin I (author)
- Landspitali Natl Univ Hosp Iceland, Iceland; Univ Iceland, Iceland
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(creator_code:org_t)
- 2021-10-03
- 2022
- English.
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In: Acta Anaesthesiologica Scandinavica. - : WILEY. - 0001-5172 .- 1399-6576. ; 66:1, s. 56-64
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Background We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID-19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID-19 disease during the first wave of COVID-19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS-CoV-2, the ratio of requiring ICU admission for COVID-19 varied substantially (1.6%-6.7%). Apart from age (proportion of patients aged 65 years or over between 29% and 62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID-19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59%-85%) in all countries, the proportion of patients receiving renal replacement therapy (7%-26%) and various experimental therapies for COVID-19 disease varied substantially (e.g. use of hydroxychloroquine 0%-85%). Crude ICU mortality ranged from 11% to 33%. Conclusion There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID-19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Keyword
- COVID-19
- mortality
- Nordic
- SARS-CoV2
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Chew, Michelle
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Kattainen, Salla
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Haase, Nicolai
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Buanes, Eirik A.
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Kristinsdottir, ...
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Hofso, Kristin
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Laake, Jon Henri ...
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Kvale, Reidar
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Hastbacka, Johan ...
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Reinikainen, Mat ...
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Bendel, Stepani
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Varpula, Tero
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Walther, Sten
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Perner, Anders
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Flaatten, Hans K ...
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Sigurdsson, Mart ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Anesthesiology a ...
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Acta Anaesthesio ...
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Linköping University