Search: onr:"swepub:oai:DiVA.org:liu-180911" > Management and outc...
Fältnamn | Indikatorer | Metadata |
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000 | 06371naa a2200781 4500 | |
001 | oai:DiVA.org:liu-180911 | |
003 | SwePub | |
008 | 211109s2021 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:147952739 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1809112 URI |
024 | 7 | a https://doi.org/10.1186/s12877-021-02476-42 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1479527392 URI |
040 | a (SwePub)liud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bruno, Raphael Romanou Heinrich Heine Univ Duesseldorf, Germany4 aut |
245 | 1 0 | a Management and outcomes in critically ill nonagenarian versus octogenarian patients |
264 | c 2021-10-19 | |
264 | 1 | b BMC,c 2021 |
338 | a electronic2 rdacarrier | |
500 | a Funding Agencies|Western Health region in Norway; Projekt DEAL | |
520 | a Background: Intensive care unit (ICU) patients age 90 years or older represent a growing subgroup and place a huge financial burden on health care resources despite the benefit being unclear. This leads to ethical problems. The present investigation assessed the differences in outcome between nonagenarian and octogenarian ICU patients. Methods: We included 7900 acutely admitted older critically ill patients from two large, multinational studies. The primary outcome was 30-day-mortality, and the secondary outcome was ICU-mortality. Baseline characteristics consisted of frailty assessed by the Clinical Frailty Scale (CFS), ICU-management, and outcomes were compared between octogenarian (80-89.9 years) and nonagenarian (>= 90 years) patients. We used multilevel logistic regression to evaluate differences between octogenarians and nonagenarians. Results: The nonagenarians were 10% of the entire cohort. They experienced a higher percentage of frailty (58% vs 42%; p < 0.001), but lower SOFA scores at admission (6 +/- 5 vs. 7 +/- 6; p < 0.001). ICU-management strategies were different. Octogenarians required higher rates of organ support and nonagenarians received higher rates of life-sustaining treatment limitations (40% vs. 33%; p < 0.001). ICU mortality was comparable (27% vs. 27%; p = 0.973) but a higher 30-day-mortality (45% vs. 40%; p = 0.029) was seen in the nonagenarians. After multivariable adjustment nonagenarians had no significantly increased risk for 30-day-mortality (aOR 1.25 (95% CI 0.90-1.74; p = 0.19)). Conclusion: After adjustment for confounders, nonagenarians demonstrated no higher 30-day mortality than octogenarian patients. In this study, being age 90 years or more is no particular risk factor for an adverse outcome. This should be considered- together with illness severity and pre-existing functional capacity - to effectively guide triage decisions. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Omvårdnad0 (SwePub)303052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nursing0 (SwePub)303052 hsv//eng |
653 | a Octogenarians; Nonagenarians; Frailty; Intensive care medicine; Outcome | |
700 | 1 | a Wernly, Bernhardu Paracelsus Med Univ, Austria; Karolinska Univ Hosp, Sweden4 aut |
700 | 1 | a Kelm, Malteu Heinrich Heine Univ Duesseldorf, Germany; Cardiovasc Res Inst Dusseldorf, Germany4 aut |
700 | 1 | a Boumendil, Arianeu St Hop Paris, France4 aut |
700 | 1 | a Morandi, Alessandrou Dept Rehabil Hosp Ancelle Cremona, Italy; Geriatr Res Grp, Italy4 aut |
700 | 1 | a Andersen, Finn H.u Alesund Hosp, Norway; NTNU, Norway4 aut |
700 | 1 | a Artigas, Antoniou CIBERes Corporac Sanitaria Univ Parc Tau, Spain4 aut |
700 | 1 | a Finazzi, Stefanou Ist Ric Farmacol Mario Negri IRCCS, Italy4 aut |
700 | 1 | a Cecconi, Mauriziou Humanitas Univ, Italy4 aut |
700 | 1 | a Christensen, Steffenu Aarhus Univ Hosp, Denmark4 aut |
700 | 1 | a Faraldi, Loredanau Grande Osped Metropolitano Niguarda, Italy4 aut |
700 | 1 | a Lichtenauer, Michaelu Paracelsus Med Univ, Austria4 aut |
700 | 1 | a Muessig, Johanna M.u Heinrich Heine Univ Duesseldorf, Germany4 aut |
700 | 1 | a Marsh, Brianu Mater Misericordiae Univ Hosp, Ireland4 aut |
700 | 1 | a Moreno, Ruiu Univ Lisboa Cent, Portugal4 aut |
700 | 1 | a Oeyen, Sandrau 1K12 Ghent Univ Hosp, Belgium4 aut |
700 | 1 | a ohman, Christina Agvaldu Karolinska Univ Hosp, Sweden4 aut |
700 | 1 | a Pinto, Bernardo Bollenu Geneva Univ Hospitals, Switzerland4 aut |
700 | 1 | a Soliman, Ivo W.u Univ Utrecht, Netherlands4 aut |
700 | 1 | a Szczeklik, Wojciechu Jagiellonian Univ, Poland4 aut |
700 | 1 | a Valentin, Andreasu Kardinal Schwarzenberg Hosp, Austria4 aut |
700 | 1 | a Watson, Ximenau St Georges Univ Hosp, England4 aut |
700 | 1 | a Leaver, Susannahu Res Lead Critical Care Directorate St Georges Hos, England4 aut |
700 | 1 | a Boulanger, Caroleu Royal Devon & Exeter NHS Fdn Trust, England4 aut |
700 | 1 | a Walther, Stenu Region Östergötland, Thorax-kärlkliniken i Östergötland4 aut0 (Swepub:liu)stewa50 |
700 | 1 | a Schefold, Joerg C.u Univ Bern, Switzerland4 aut |
700 | 1 | a Joannidis, Michaelu Med Univ Innsbruck, Austria4 aut |
700 | 1 | a Nalapko, Yuriyu ICU, Ukraine4 aut |
700 | 1 | a Elhadi, Muhammedu Alkhums Hosp, Libya4 aut |
700 | 1 | a Fjolner, Jesperu Aarhus Univ Hosp, Denmark4 aut |
700 | 1 | a Zafeiridis, Tilemachosu Gen Hosp Larissa, Greece4 aut |
700 | 1 | a De Lange, Dylan W.u Univ Utrecht, Netherlands4 aut |
700 | 1 | a Guidet, Bertrandu St Hop Paris, France; Sorbonne Univ, France; INSERM, France4 aut |
700 | 1 | a Flaatten, Hansu Univ Bergen, Norway; Haukeland Hosp, Norway4 aut |
700 | 1 | a Jung, Christianu Heinrich Heine Univ Duesseldorf, Germany4 aut |
710 | 2 | a Heinrich Heine Univ Duesseldorf, Germanyb Paracelsus Med Univ, Austria; Karolinska Univ Hosp, Sweden4 org |
773 | 0 | t BMC Geriatricsd : BMCg 21:1q 21:1x 1471-2318 |
856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1609703/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://bmcgeriatr.biomedcentral.com/track/pdf/10.1186/s12877-021-02476-4 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-180911 |
856 | 4 8 | u https://doi.org/10.1186/s12877-021-02476-4 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:147952739 |
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