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Social gradients in ADHD by household income and maternal education exposure during early childhood : Findings from birth cohort studies across six countries

Spencer, Nicholas James (author)
Univ Warwick, England
Ludvigsson, Johnny (author)
Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus
Bai, Guannan (author)
Univ Med Ctr Rotterdam, Netherlands
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Gauvin, Lise (author)
Ctr Hosp Univ Montreal, Canada; Univ Montreal, Canada
Clifford, Susan A. (author)
Univ Melbourne, Australia; Univ Melbourne, Australia
Abu Awad, Yara (author)
Concordia Univ, Canada
Goldhaber-Fiebert, Jeremy D. (author)
Stanford Univ, CA USA
Markham, Wolfgang (author)
Univ Warwick, England
Olsen Faresjö, Åshild (author)
Linköpings universitet,Avdelningen för samhälle och hälsa,Medicinska fakulteten
Andersson White, Pär (author)
Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus
Raat, Hein (author)
Univ Med Ctr Rotterdam, Netherlands
Jansen, Pauline (author)
Univ Med Ctr Rotterdam, Netherlands; Univ Med Ctr Rotterdam, Netherlands
Nikiema, Beatrice (author)
Ctr Hosp Univ Montreal, Canada; Cree Board Hlth Social Serv James Bay, Canada
Mensah, Fiona K. (author)
Univ Melbourne, Australia; Univ Melbourne, Australia
McGrath, Jennifer J. (author)
Concordia Univ, Canada
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 (creator_code:org_t)
2022-03-16
2022
English.
In: PLOS ONE. - : Public Library of Science. - 1932-6203. ; 17:3
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • ObjectiveThis study aimed to examine social gradients in ADHD during late childhood (age 9-11 years) using absolute and relative relationships with socioeconomic status exposure (household income, maternal education) during early childhood (<5 years) in seven cohorts from six industrialised countries (UK, Australia, Canada, The Netherlands, USA, Sweden). MethodsSecondary analyses were conducted for each birth cohort. Risk ratios, pooled risk estimates, and absolute inequality, measured by the Slope Index of Inequality (SII), were estimated to quantify social gradients in ADHD during late childhood by household income and maternal education measured during early childhood. Estimates were adjusted for child sex, mother age at birth, mother ethnicity, and multiple births. FindingsAll cohorts demonstrated social gradients by household income and maternal education in early childhood, except for maternal education in Quebec. Pooled risk estimates, relating to 44,925 children, yielded expected gradients (income: low 1.83(CI 1.38,2.41), middle 1.42(1.13,1.79), high (reference); maternal education: low 2.13(1.39,3.25), middle 1.42(1.13,1.79)). Estimates of absolute inequality using SII showed that the largest differences in ADHD prevalence between the highest and lowest levels of maternal education were observed in Australia (4% lower) and Sweden (3% lower); for household income, the largest differences were observed in Quebec (6% lower) and Canada (all provinces: 5% lower). ConclusionFindings indicate that children in families with high household income or maternal education are less likely to have ADHD at age 9-11. Absolute inequality, in combination with relative inequality, provides a more complete account of the socioeconomic status and ADHD relationship in different high-income countries. While the study design precludes causal inference, the linear relation between early childhood social circumstances and later ADHD suggests a potential role for policies that promote high levels of education, especially among women, and adequate levels of household income over childrens early years in reducing risk of later ADHD.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

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