Measurement uncertainty for practical use

Coskun, Abdurrahman (author): EFLM Task & Finish Grp Pract Approach Measurement, Italy; Acibadem Mehmet Ali Aydinlar Univ, Turkey

Theodorsson, Elvar (author): Linköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, Klinisk kemi,EFLM Task & Finish Grp Pract Approach Measurement, Italy

Oosterhuis, Wytze P. (author): EFLM Task & Finish Grp Pract Approach Measurement, Italy; Reinier Haga Med Diagnost Ctr, Netherlands

Sandberg, Sverre (author): EFLM Task & Finish Grp Pract Approach Measurement, Italy; Haraldsplass Diaconess Hosp, Norway; Univ Bergen, Norway

(creator_code:org_t)

ELSEVIER, 2022
2022
English.
In: Clinica Chimica Acta. - : ELSEVIER. - 0009-8981 .- 1873-3492. ; 531, s. 352-360

Related links:: https://urn.kb.se/re...; show more...; https://doi.org/10.1...; show less...

Abstract Subject headings

Uncertainty is an inseparable part of all kinds of measurements performed in clinical laboratories. Accreditation standards including the ISO/IEC 17025:2017 and ISO 15189:2012 require that laboratories have routines for calculating the measurement uncertainty of reported results. Various guidelines such as CLSI EP29, Nordest 537, and ISO 20914:2019 have proposed methods for this purpose. However, due to the conceived complexity of the proposed calculation methods, these guidelines have not been generally and effectively applied in clinical laboratories. High workload and measurand heterogeneity favor a pragmatic utilitarian approach. The purpose of this paper is to describe such an approach, including its advantages and disadvantages. Measurement uncertainty should include the most influential factors affecting patients test results. Since patients samples for the same measurand can be analyzed in one laboratory or several laboratories using different measuring systems, the measurement uncertainty should be calculated using results obtained from analyzing the same internal quality control material if commutable or patients pooled/split samples.

By the author/editor: Coskun, Abdurrah ...; Theodorsson, Elv ...; Oosterhuis, Wytz ...; Sandberg, Sverre

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Laborato ...

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