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  • Fronczek, JakubJagiellonian Univ Med Coll, Poland (author)

Short-term mortality or patients >= 80 years old admitted to European intensive care units: an international observational study

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • ELSEVIER SCI LTD,2022
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-188157
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-188157URI
  • https://doi.org/10.1016/j.bja.2022.03.026DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies|Polish National Agency for Academic Exchange, Iwanowska Programme [PPN/IWA/2019/1/00106]; Polpharma Scientific Foundation
  • Background: Limited evidence suggests variation in mortality of older critically ill adults across Europe. We aimed to investigate regional differences in mortality among very old ICU patients. Methods: Multilevel analysis of two international prospective cohort studies. We included patients >= 80 yr old from 322 ICUs located in 16 European countries. The primary outcome was mortality within 30 days from admission to the ICU. Results are presented as n (%) with 95% confidence intervals and odds ratios (ORs). Results: Of 8457 patients, 2944 (36.9% [35.9-38.0%]) died within 30 days. Crude mortality rates varied widely between participating countries (from 10.1% [6.4-15.6%] to 45.1% [41.1-49.2%] in the ICU and from 21.3% [16.3-28.9%] to 55.3% [51.1-59.5%] within 30 days). After adjustment for confounding variables, the variation in 30-day mortality between countries was substantially smaller than between ICUs (median OR 1.14 vs 1.58). Healthcare expenditure per capita (OR=0.84 per $1000 [0.75-0.94]) and social health insurance framework (OR=1.43 [1.01-2.01]) were associated with ICU mortality, but the direction and magnitude of these relationships was uncertain in 30-day follow-up. Volume of admissions was associated with lower mortality both in the ICU (OR=0.81 per 1000 annual ICU admissions [0.71-0.94]) and in 30-day follow-up (OR=0.86 [0.76-0.97]). Conclusion: The apparent variation in short-term mortality rates of older adults hospitalised in ICUs across Europe can be largely attributed to differences in the clinical profile of patients admitted. The volume-outcome relationship identified in this population requires further investigation.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Flaatten, HansHaukeland Hosp, Norway; Univ Bergen, Norway (author)
  • Guidet, BertrandUPMC Univ Paris 06, France; Hop St Antoine, France (author)
  • Polok, KamilJagiellonian Univ Med Coll, Poland (author)
  • Andersen, Finn H.Alesund Hosp, Norway; NTNU, Norway (author)
  • Andrew, Benjamin Y.Duke Univ, NC 27710 USA (author)
  • Artigas, AntonioAutonomous Univ Barcelona, Spain (author)
  • Beil, MichaelHadassah Med Ctr, Israel (author)
  • Cecconi, MaurizioHumanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ, Italy (author)
  • Christensen, SteffenAarhus Univ Hosp, Denmark (author)
  • de Lange, Dylan W.Univ Utrecht, Netherlands (author)
  • Fjolner, JesperAarhus Univ Hosp, Denmark (author)
  • Gorka, JacekJagiellonian Univ Med Coll, Poland (author)
  • Joannidis, MichaelMed Univ Innsbruck, Austria (author)
  • Jung, ChristianHeinrich Heine Univ, Germany (author)
  • Kusza, KrzysztofPoznan Univ Med Sci, Poland (author)
  • Leaver, SusannahSt George Hosp, England (author)
  • Marsh, BrianMater Misericordiae Univ Hosp, Ireland (author)
  • Morandi, AlessandroGeriatr Res Grp, Italy (author)
  • Moreno, RuiCtr Hosp Univ Lisboa Cent, Portugal (author)
  • Oeyen, SandraGhent Univ Hosp, Belgium (author)
  • Owczuk, RadoslawMed Univ Gdansk, Poland (author)
  • Agvald-Ohman, ChristinaKarolinska Univ Hosp, Sweden (author)
  • Pinto, Bernardo B.Geneva Univ Hosp, Switzerland (author)
  • Rhodes, AndrewSt Georges Univ Hosp NHS Fdn Trust, England (author)
  • Schefold, Joerg C.Univ Bern, Switzerland (author)
  • Soliman, Ivo W.Univ Utrecht, Netherlands (author)
  • Valentin, AndreasKardinal Schwarzenberg Hosp, Austria (author)
  • Walther, StenLinköpings universitet,Medicinska fakulteten,Institutionen för hälsa, medicin och vård,Region Östergötland, Thorax-kärlkliniken i Östergötland,Region Östergötland, ANOPIVA US(Swepub:liu)stewa50 (author)
  • Watson, XimenaSt Georges Univ Hosp NHS Fdn Trust, England (author)
  • Zafeiridis, TilemachosGen Hosp Larissa, Greece (author)
  • Szczeklik, WojciechJagiellonian Univ Med Coll, Poland (author)
  • Jagiellonian Univ Med Coll, PolandHaukeland Hosp, Norway; Univ Bergen, Norway (creator_code:org_t)

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  • In:British Journal of Anaesthesia: ELSEVIER SCI LTD129:1, s. 58-660007-09121471-6771

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