Search: onr:"swepub:oai:DiVA.org:liu-189448" >
Clinical Outcomes A...
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Latenstein, Anouk E. J.Univ Amsterdam, Netherlands
(author)
Clinical Outcomes After Total Pancreatectomy A Prospective Multicenter Pan-European Snapshot Study
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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LIPPINCOTT WILLIAMS & WILKINS,2022
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Numbers
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LIBRIS-ID:oai:DiVA.org:liu-189448
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-189448URI
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https://doi.org/10.1097/SLA.0000000000004551DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Objective: To assess outcomes among patients undergoing total pancreatectomy (TP) including predictors for complications and in-hospital mortality. Background: Current studies on TP mostly originate from high-volume centers and span long time periods and therefore may not reflect daily practice. Methods: This prospective pan-European snapshot study included patients who underwent elective (primary or completion) TP in 43 centers in 16 European countries (June 2018-June 2019). Subgroup analysis included cutoff values for annual volume of pancreatoduodenectomies (<60 vs >= 60). Predictors for major complications and in-hospital mortality were assessed in multivariable logistic regression. Results: In total, 277 patients underwent TP, mostly for malignant disease (73%). Major postoperative complications occurred in 70 patients (25%). Median hospital stay was 12 days (IQR 9-18) and 40 patients were readmitted (15%). In-hospital mortality was 5% and 90-day mortality 8%. In the subgroup analysis, in-hospital mortality was lower in patients operated in centers with >= 60 pancreatoduodenectomies compared <60 (4% vs 10%, P = 0.046). In multivariable analysis, annual volume <60 pancreatoduodenectomies (OR 3.78, 95% CI 1.18-12.16, P = 0.026), age (OR 1.07, 95% CI 1.01-1.14, P = 0.046), and estimated blood loss >= 2L (OR 11.89, 95% CI 2.64-53.61, P = 0.001) were associated with in-hospital mortality. ASA >= 3 (OR 2.87, 95% CI 1.56-5.26, P = 0.001) and estimated blood loss >= 2L (OR 3.52, 95% CI 1.25-9.90, P = 0.017) were associated with major complications. Conclusion: This pan-European prospective snapshot study found a 5% inhospital mortality after TP. The identified predictors for mortality, including low-volume centers, age, and increased blood loss, may be used to improve outcomes.
Subject headings and genre
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Scholten, LianneUniv Amsterdam, Netherlands
(author)
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Al-Saffar, Hasan AhmadKarolinska Univ Hosp, Sweden
(author)
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Björnsson, BergthorLinköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US(Swepub:liu)berbj34
(author)
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Butturini, GiovanniPederzoli Hosp, Italy
(author)
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Capretti, GiovanniHumanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ Dept Biomed Sci, Italy
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Chatzizacharias, Nikolaos A.Univ Hosp Birmingham NHS Trust, England
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Dervenis, ChrisUniv Cyprus, Cyprus
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Frigerio, IsabellaPederzoli Hosp, Italy
(author)
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Gallagher, Tom K.St Vincents Univ Hosp, Ireland
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Gasteiger, SilviaMed Univ Innsbruck, Austria
(author)
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Halimi, AsifKarolinska Univ Hosp, Sweden
(author)
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Labori, Knut J.Oslo Univ Hosp, Norway
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Montagnini, GretaUniv & Hosp Trust Verona, Italy
(author)
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Munoz-Bellvis, LuisUniv Salamanca, Spain
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Nappo, GennaroHumanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ Dept Biomed Sci, Italy
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Nikov, AndrejCent Mil Hosp Prague, Czech Republic
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Pando, ElizabethHosp Valle De Hebron, Spain
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de Pastena, MatteoUniv & Hosp Trust Verona, Italy
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De La Pena-Moral, Jesus M.Hosp Clin Univ Virgen Arrixaca, Spain
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Radenkovic, DejanUniv Belgrade, Serbia
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Roberts, Keith J.Univ Hosp Birmingham NHS Trust, England
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Salvia, RobertoUniv & Hosp Trust Verona, Italy
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Sanchez-Bueno, FranciscoHosp Clin Univ Virgen Arrixaca, Spain
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Scandavini, ChiaraKarolinska Univ Hosp, Sweden
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Serradilla-Martin, MarioMiguel Servet Univ Hosp, Spain
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Stattner, StefanMed Univ Innsbruck, Austria; Salzkammergut Klinikum, Austria
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Tomazic, AlesUniv Med Ctr Ljubljana, Slovenia
(author)
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Varga, MartinParacelsus Med Univ, Austria
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Zavrtanik, HanaUniv Med Ctr Ljubljana, Slovenia
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Zerbi, AlessandroHumanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ Dept Biomed Sci, Italy
(author)
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Erkan, MertKoc Univ, Turkey
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Kleeff, JorgMartin Luther Univ Halle Wittenberg, Germany
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Lesurtel, MickaelUniv Lyon 1, France
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Besselink, Marc G.Univ Amsterdam, Netherlands
(author)
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Ramia-Angel, Jose M.Univ Hosp Guadalajara, Spain
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Univ Amsterdam, NetherlandsKarolinska Univ Hosp, Sweden
(creator_code:org_t)
Related titles
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In:Annals of Surgery: LIPPINCOTT WILLIAMS & WILKINS276:5, s. E536-E5430003-49321528-1140
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Latenstein, Anou ...
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Scholten, Lianne
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Al-Saffar, Hasan ...
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Björnsson, Bergt ...
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Butturini, Giova ...
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Capretti, Giovan ...
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Chatzizacharias, ...
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Dervenis, Chris
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Frigerio, Isabel ...
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Gasteiger, Silvi ...
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Halimi, Asif
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Labori, Knut J.
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Montagnini, Gret ...
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Munoz-Bellvis, L ...
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Nappo, Gennaro
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Nikov, Andrej
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Pando, Elizabeth
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de Pastena, Matt ...
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De La Pena-Moral ...
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Radenkovic, Deja ...
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Roberts, Keith J ...
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Salvia, Roberto
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Sanchez-Bueno, F ...
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Scandavini, Chia ...
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Serradilla-Marti ...
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Stattner, Stefan
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Tomazic, Ales
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Varga, Martin
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Zavrtanik, Hana
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Zerbi, Alessandr ...
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Erkan, Mert
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Kleeff, Jorg
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Lesurtel, Mickae ...
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Besselink, Marc ...
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Ramia-Angel, Jos ...
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