onr:"swepub:oai:DiVA.org:liu-193386"
Search: onr:"swepub:oai:DiVA.org:liu-193386" > Impact of dobutamin...
- 1 of 1
- Previous record
- Next record
- To hitlist
Impact of dobutamine stress on diastolic energetic efficiency of healthy left ventricle: an in vivo kinetic energy analysis
-
- Riva, Alessandra (author)
- Politecn Milan, Italy; Policlin San Donato, Italy
-
- Eriksson, Jonatan (author)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Medicinsk strålningsfysik
-
- Viola, Federica (author)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten
- show more...
- show less...
- (creator_code:org_t)
- 2023-03-21
- 2023
- English.
- In: Frontiers in Cardiovascular Medicine. - : FRONTIERS MEDIA SA. - 2297-055X. ; 10
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The total kinetic energy (KE) of blood can be decomposed into mean KE (MKE) and turbulent KE (TKE), which are associated with the phase-averaged fluid velocity field and the instantaneous velocity fluctuations, respectively. The aim of this study was to explore the effects of pharmacologically induced stress on MKE and TKE in the left ventricle (LV) in a cohort of healthy volunteers. 4D Flow MRI data were acquired in eleven subjects at rest and after dobutamine infusion, at a heart rate that was similar to 60% higher than the one in rest conditions. MKE and TKE were computed as volume integrals over the whole LV and as data mapped to functional LV flow components, i.e., direct flow, retained inflow, delayed ejection flow and residual volume. Diastolic MKE and TKE increased under stress, in particular at peak early filling and peak atrial contraction. Augmented LV inotropy and cardiac frequency also caused an increase in direct flow and retained inflow MKE and TKE. However, the TKE/KE ratio remained comparable between rest and stress conditions, suggesting that LV intracavitary fluid dynamics can adapt to stress conditions without altering the TKE to KE balance of the normal left ventricle at rest.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Maskinteknik -- Strömningsmekanik och akustik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Mechanical Engineering -- Fluid Mechanics and Acoustics (hsv//eng)
Keyword
- 4D flow MRI; dobutamine stress; kinetic energy; left ventricle; turbulent kinetic energy; flow physiology; stress cardiovascular magnetic resonance; hemodynamics
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Frontiers in Cardiovascular Medicine (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Riva, Alessandra
- Eriksson, Jonata ...
- Viola, Federica
- Sturla, Francesc ...
- Votta, Emiliano
- Ebbers, Tino
- show more...
- Carlhäll, Carljo ...
- Dyverfeldt, Pett ...
- show less...
- About the subject
-
- ENGINEERING AND TECHNOLOGY
- ENGINEERING AND ...
- and Mechanical Engin ...
- and Fluid Mechanics ...
- Articles in the publication
- Frontiers in Car ...
- By the university
- Linköping University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
