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Excessive hair cort...
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Braenden, AstridOslo Univ Hosp, Norway; Oslo Univ Hosp, Norway
(author)
Excessive hair cortisol concentration as an indicator of psychological disorders in children
- Article/chapterEnglish2023
Publisher, publication year, extent ...
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PERGAMON-ELSEVIER SCIENCE LTD,2023
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-198480
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-198480URI
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https://doi.org/10.1016/j.psyneuen.2023.106363DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agencies|South-Eastern Norway Regional Health Authority
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Cortisol in hair is a new biomarker assessing long-term hypothalamic-pituitary-adrenal (HPA) axis activity, which is related to emotion regulation. We compare hair cortisol concentrations (HCC), in clinically referred children with disruptive mood dysregulation disorder (DMDD) (n = 19), children with other types of psychological disorders (n = 48), and healthy subjects (n = 36). We also investigate the association between HCC and irritability, age, and sex. Our results show that children with DMDD or other types of psychological disorders have higher HCC than healthy subjects, p < .001, ?(2)(p) = .39. No difference between children with DMDD and those with other types of psychological disorders was found, p = .91, nor an association between HCC and irritability in the clinical sample, p = .32. We found a significant negative correlation between HCC and age in those with DMDD, r = -0.54, p < .05, but not in the normative sample, r = -0.20, p = .25. No differences in HCC between girls and boys were found in the normative sample, p = .49. Children in need of psychological treatment, including those with DMDD, seem to have dysregulated HPA-axis activity over time. Excessive accumulated cortisol concentrations in hair could be an indicator of a psychological disorder in children.
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Added entries (persons, corporate bodies, meetings, titles ...)
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Lebena, AndreaLinköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten(Swepub:liu)andle23
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Olsen Faresjö, ÅshildLinköpings universitet,Avdelningen för samhälle och hälsa,Medicinska fakulteten(Swepub:liu)asols47
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Theodorsson, ElvarLinköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, Klinisk kemi(Swepub:liu)elvth65
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Coldevin, MaritLovisenberg Diaconal Hosp, Norway
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Stubberud, JanLovisenberg Diaconal Hosp, Norway; Univ Oslo, Norway
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Zeiner, PalOslo Univ Hosp, Norway; Univ Oslo, Norway
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Melinder, AnnikaOslo Univ Hosp, Norway; Univ Oslo, Norway
(author)
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Oslo Univ Hosp, Norway; Oslo Univ Hosp, NorwayAvdelningen för barns och kvinnors hälsa
(creator_code:org_t)
Related titles
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In:Psychoneuroendocrinology: PERGAMON-ELSEVIER SCIENCE LTD1570306-45301873-3360
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