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Pancreatic surgery ...
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Fusai, Giuseppe KitoRoyal Free Hosp, England; UCL, England
(author)
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Article/chapterEnglish2023
Publisher, publication year, extent ...
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2023
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OXFORD UNIV PRESS,2023
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-200699
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-200699URI
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https://doi.org/10.1093/bjs/znad330DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agencies|Fiorina Royal Free Charity, London, UK; Swiss Pancreas Foundation, Berne, Switzerland
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Background: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide. Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters. Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries. Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761).
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Ferrone, CristinaCedars Sinai Med Ctr, CA 90048 USA
(author)
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Raptis, Dimitri AristotleKing Faisal Specialist Hosp & Res Ctr, Saudi Arabia
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Abu Hilal, MohamedUniv Hosp Southampton, England
(author)
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Bassi, ClaudioUniv Hosp Verona, Italy
(author)
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Besselink, MarcUniv Amsterdam, Netherlands
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Conlon, KevinTrinity Coll Dublin, Ireland
(author)
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Davidson, BrianUCL, England
(author)
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Del Chiaro, MarcoUniv Colorado, CO USA
(author)
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Dervenis, ChristosMetropolitan Hosp Athens, Greece
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Frigerio, IsabellaPederzoli Clin, Italy
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Falconi, MassimoOsped San Raffaele, Italy
(author)
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Hackert, ThiloHeidelberg Univ, Germany
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Harrison, Ewen M.Univ Edinburgh, Scotland
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Shrikhande, Shailesh VTata Mem Hosp, India
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Siriwardena, AjithUniv Manchester, England
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Smith, MartinUniv Witwatersrand, South Africa
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Wolfgang, ChristopherJohns Hopkins Univ Hosp, MD 21287 USA
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Borakati, AdityaRoyal Free Hosp, England
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Balci, DenizAnkara Univ Hosp, Turkiye
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Elhadi, MuhammedUniv Tripoli, Libya; Univ Tripoli, Libya
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Salinas, Camila HidalgoRoyal Free Hosp, England
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Machairas, NikolaosRoyal Free Hosp, England
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Marchegiani, GiovanniUniv Hosp Verona, Italy
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Oba, AtsushiUniv Colorado, CO USA
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Oberkofler, ChristianUniv Hosp Zurich, Switzerland
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Passas, IoannisMetropolitan Hosp Athens, Greece
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Ravikumar, ReenaRoyal Infirm Edinburgh NHS Trust, Scotland
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Sanchez Velazquez, PatriciaUniv Hosp del Mar, Spain
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de Santibanes, MartinItalian Hosp Buenos Aires, Argentina
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Schnitzbauer, Andreas AntonUniv Hosp Frankfurt, Germany
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Soggiu, FiammettaRoyal Free Hosp, England
(author)
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Tamburrino, DomenicoOsped San Raffaele, Italy
(author)
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Tinguely, PascaleRoyal Free Hosp, England
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Wei, AliceMem Sloan Kettering Canc, NY USA
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Zachiotis, MarinosUniv Patras, Greece
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Bentabak, KamelPierre & Marie Curie Canc Ctr, Algeria
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Kacimi, Salah EddineUniv Tlemcen, Algeria
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Nikfarjam, MehrdadUniv Melbourne, Australia
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Shcherba, AliakseiMinsk Med Ctr Surg, BELARUS
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Sergeant, GregoryJessa Ziekenhuis Hasselt, Belgium
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Coelho, GustavoFed Univ Ceara Fortaleza, Brazil
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Torres, OrlandoMaranhao Fed Univ Sao Luis, Brazil
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Belev, NikolayMU Plovdiv, Bulgaria
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Fabrice, BurundiMuhezagiro Univ Burundi, Burundi
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Tang, EphraimWestern Univ London, Canada
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Martin, JanetWestern Univ London, Canada
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Diaz, ChristianHosp Dr Sotero del Rio, Chile
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Devaud, NicolasFdn Arturo Lopez Perez FALP, Chile
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Wei, KongyuanHeidelberg Univ Hosp, Germany; Chinese Peoples Liberat Army Gen Hosp, Peoples R China
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Hendi, MaherZhejiang Univ, Peoples R China
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Mikulic, DankoUniv Hosp Merkur Zagreb, Croatia
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Gouvas, NikolaosUniv Cyprus, Cyprus
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Christophides, ThalisNicosia Gen Hosp, Cyprus
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Nikov, AndrejUniv Hosp Kralovske Vinohrady, Czech Republic
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Fathallah, DaliaAlexandria Univ, Egypt
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Saad, MahmoudAssiut Fac Med, Egypt
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Tammik, OlavUniv Clin Tartu, Estonia
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Huhta, HeikkiOulu Univ Hosp, Finland
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Sulpice, LaurentUniv Hosp Rennes, France
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Lupinacci, RenatoParis Saclay Univ, France
(author)
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Demetrashvili, ZazaTbilisi State Med Univ, Georgia
(author)
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Stavrou, Gregor A.Klinikum Saarbrucken, Germany
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Felekouras, EvangelosNatl & Kapodistrian Univ Athens, Greece
(author)
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Papaziogas, VasileiosAristotle Univ Thessaloniki, Greece
(author)
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Misra, SanjeevAll India Inst Med Sci Jodhpur, India
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Diponegoro, Erik PrabowoUniv Kariadi, Indonesia
(author)
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Hashim, Hashim TalibUniv Baghdad, Iraq
(author)
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Al-Sader, Maytham Al-JuaifariTeaching Hosp, Iraq
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Satoi, SoheiKansai Med Univ Hirakata, Japan
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Obeidat, KhaledJordan Univ Sci & Technol, Jordan
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Mohsen, MaramJordan Univ Hosp, Jordan
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Fakhradiyev, Ildar
(author)
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Han, Ho-SeongSeoul Natl Univ, South Korea
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Khalife, MohamadAmer Univ Beirut, Lebanon
(author)
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Dulskas, AudriusNatl Canc Inst Vilnius, Lithuania
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Bong, JinSunway Med Ctr Petaling Jaya, Malaysia
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Ghani, ShahiTree Top Hosp, Maldives
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Eduardo Padilla, AlejandroRosciano Natl Canc Inst, Mexico
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Melchor-Ruan, JavierNatl Canc Inst Mexico, Mexico
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Erdene, SarnaiMongolian Natl Univ Med Sci, Mongolia
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Benkabbou, AmineMohammed Univ Rabat, Morocco
(author)
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Nashidengo, PueyaUniv Namibia, Namibia
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Koea, JonathanNorth Shore Hosp, New Zealand
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Adeyeye, AdemolaUniv Ado Ekiti ABUAD, Nigeria
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Alatise, OlusegunObafemi Awolowo Univ, Nigeria
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Ullah, SamiServ Hosp Lahore, Pakistan
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Abu Jayyab, MustafaAlshifaa Hosp, Palestine
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Amro, SarahAlia Govt Hosp, Palestine
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Alnammourah, Walaa MohammedAlia Govt Hosp, Palestine
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The, CatherineMakati Med Ctr, Palestine
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Pedziwiatr, MichalJagiellonian Univ Med Coll, Poland
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Polkowski, WojciechMed Univ Lublin, Poland
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Barbu, Sorin TraianIuliu Hatieganu Univ Med & Pharm, Romania
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Karamarkovic, AleksandarUniv Clin Ctr Zvezdara, Serbia; Univ Belgrade, Serbia
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Galun, DanielClin Ctr Serbia, Serbia
(author)
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Goh, Brian K. P.Singapore Gen Hosp, Singapore
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Trotovsek, BlazUniv Med Ctr Ljubljana, Slovenia
(author)
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Omoshoro-Jones, JonesUniv Witwatersrand, South Africa
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Ielpo, BenedettoHosp del Mar, Spain
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Abdelmageed, AbdelfatahOmdurman Islamic Univ, Sudan
(author)
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Sandström, Per A,1965-Linköpings universitet,Medicinska fakulteten,Avdelningen för kirurgi, ortopedi och onkologi,Region Östergötland, Kirurgiska kliniken US(Swepub:liu)persa07
(author)
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Cristaudi, AlessandraOsped Reg Lugano, Switzerland
(author)
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Gloor, BeatUniv Bern, Switzerland
(author)
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Kuemmerli, ChristophSt Clara Hosp, Switzerland; Univ Hosp Basel, Switzerland
(author)
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Tishreen, Alaa HamdanUniv Hosp Lattakia, Syria
(author)
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Chaaban, Mohammad KaramAl Mouwasat Univ Hosp, Syria
(author)
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Wu, Chien HuiNatl Taiwan Univ Hosp, Taiwan
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Jen, Po-Chih Yang FuCatholic Univ Hosp, Taiwan
(author)
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Houssem, AmmarSahloul Hosp, Tunisia
(author)
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Baraket, OussamaUniv Tunis El Labar Bizerte, Tunisia
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Coker, AhmetEge Univ, Turkiye
(author)
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Taylor, MarkBelfast Hlth & Social Care Trust, North Ireland
(author)
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Jamieson, NigelUniv Glasgow, Scotland
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Iype, SatheeshRoyal Free Hosp London, England
(author)
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Giorgakis, EmmanouilUAMS Med Ctr, AR USA
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Qadan, MotazMassachusetts Gen Hosp, MA 02114 USA
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Ganai, SabhaUniv North Dakota, ND USA
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Al-Naggar, HamzaSanaa Univ, Yemen
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Chihaka, OnesaiUniv Zimbabwe, Zimbabwe
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Royal Free Hosp, England; UCL, EnglandCedars Sinai Med Ctr, CA 90048 USA
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In:British Journal of Surgery: OXFORD UNIV PRESS0007-13231365-2168
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